Evidence map›Paper›PMID 42598431›Full record

ArticleACS omega2026

Indole-2-carboxylic Acid Nanoemulsions: A Novel Approach for Topical Cosmeceuticals with Antioxidant Properties in Human Skin Models.

Hyanne Pereira Lima, Eduarda Pires Costa, Gislaine Gonçalves Fonseca, Nathan Caraciole Brito, Manoela Maciel Dos Santos Dias, Jemmyson Romário de Jesus, Tatianny de Araújo Andrade, Gaspar Diaz Muñoz, Carlos Eduardo Soares Gazzinelli Cruz, Reggiani Vilela Gonçalves and 1 more

Abstract read
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In one paragraph

Article in ACS omega, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Hyanne Pereira LimaDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Eduarda Pires CostaDepartment of General Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0009-0002-8817-8067
Gislaine Gonçalves FonsecaDepartment of Chemistry, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Nathan Caraciole BritoDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Manoela Maciel Dos Santos DiasDepartment of Animal Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Jemmyson Romário de JesusDepartment of Chemistry, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0000-0001-9761-0275
Tatianny de Araújo AndradeDepartment of Chemistry, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Gaspar Diaz MuñozDepartment of Chemistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais 31270-901, Brazil.
Carlos Eduardo Soares Gazzinelli CruzDepartment of General Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Reggiani Vilela GonçalvesDepartment of Animal Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.
Marisa Alves Nogueira DiazDepartment of Biochemistry and Molecular Biology, Federal University of Viçosa, Avenida PH Rolfs, s/n, Campus Universitário, Viçosa, Minas Gerais 36570-900, Brazil.ORCID https://orcid.org/0000-0002-3370-4149

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bioactive molecules, such as indole alkaloids, have received special attention due to their remarkable pharmacological versatility, particularly their antioxidant activities. Therefore, our objective was to build an engineered delivery system (a topical nanoemulsion), incorporating indole-2-carboxylic acid, and evaluate its antioxidant potential using an

Identifiers

PMID42598431
PMCPMC13470833

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.