Evidence map›Paper›PMID 42598424›Full record

ArticleAmerican journal of ophthalmology case reports2026

Acrylic intraocular lenses in patients with patch test-confirmed acrylate allergy: two cases with 1-year follow-up.

Daisuke Nakata, Motohiro Kamei, Taisei Ishio, Kyoko Futamura, Akiko Yagami, Yasuki Ito, Atsuhiro Tanikawa

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In one paragraph

Article in American journal of ophthalmology case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Daisuke NakataDepartment of Ophthalmology, Fujita Health University, School of Medicine, Toyoake, Japan.
Motohiro KameiDepartment of Ophthalmology, Aichi Medical University, Nagakute, Japan.
Taisei IshioDepartment of Ophthalmology, Aichi Medical University, Nagakute, Japan.
Kyoko FutamuraDepartment of Allergology, Fujita Health University School of Medicine, Toyoake, Japan.
Akiko YagamiDepartment of Allergology, Fujita Health University School of Medicine, Toyoake, Japan.
Yasuki ItoDepartment of Ophthalmology, Fujita Health University, School of Medicine, Toyoake, Japan.
Atsuhiro TanikawaDepartment of Ophthalmology, Fujita Health University, School of Medicine, Toyoake, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: To report our experience with two cases of acrylate allergy confirmed by patch testing, wherein acrylic intraocular lens (IOL) implantation was performed and followed up for 1 year. Observations: A 78-year-old woman with an allergy to acrylic resin consulted a general allergist because of suspected depigmented contact dermatitis. A patch test was positive for methyl methacrylate and 2-hydroxyethyl methacrylate (2-HEMA), which are acrylic resins. Before cataract surgery, patch tests for the IOL and other acrylic resin materials were performed, all of which tested negative. Case 2: A 49-year-old woman was allergic to several substances, including acrylic resin. A patch test was positive for 2-HEMA and ethylene glycol dimethacrylate. We consulted an anesthesiologist regarding immediate-type allergy and explained to the patient about the possibility of IOL removal for delayed-type allergy. Intra-or postoperative complications were not observed in either patient. Postoperative inflammation was similar to that observed after conventional cataract surgeries. During the 1-year follow-up period, worsening of inflammation in the anterior chamber or other symptoms indicative of delayed hypersensitivity were not observed. Conclusions and importance: In two patients with cutaneous acrylate allergy, hydrophobic acrylic IOL implantation was uneventful through the 1-year follow-up period. Careful preoperative patch testing, allergist collaboration, informed consent about uncertain long-term risk, and close follow-up are advised.

Indexed as

Acrylic resinCutaneous delayed-type hypersensitivityEndophthalmitisIntraocular lens (IOL)Patch testToxic anterior segment syndrome (TASS)

Identifiers

PMID42598424
PMCPMC13471059

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