Evidence map›Paper›PMID 42598408›Full record

ArticlePulmonary circulation2026

Transitions From Parenteral Prostacyclin Analogues to Selexipag in Patients With Pulmonary Arterial Hypertension.

Dalton J Kuebel, Adele R Collins, Arun Jose, Maria R Guido, Jean M Elwing

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pulmonary circulation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dalton J KuebelDivision of Pharmacy Practice and Administrative Sciences University of Cincinnati James L. Winkle College of Pharmacy Cincinnati Ohio USA.ORCID https://orcid.org/0000-0002-2782-1322
Adele R CollinsDivision of Internal Medicine University of Cincinnati Cincinnati Ohio USA.
Arun JoseDivision of Pulmonary, Critical Care, and Sleep Medicine University of Cincinnati Cincinnati Ohio USA.ORCID https://orcid.org/0000-0001-7109-2692
Maria R GuidoDivision of Pharmacy Practice and Administrative Sciences University of Cincinnati James L. Winkle College of Pharmacy Cincinnati Ohio USA.
Jean M ElwingDivision of Pulmonary, Critical Care, and Sleep Medicine University of Cincinnati Cincinnati Ohio USA.ORCID https://orcid.org/0000-0001-6199-1707

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pulmonary arterial hypertension (PAH) is a progressive illness that may require therapy with parenteral prostacyclin pathway agents (PPA) (epoprostenol and treprostinil). These parenteral PPA's are continuous ambulatory infusions that require a high level of skill and knowledge to maintain safety and effectiveness. Depending on the clinical context, transition to oral prostacyclin receptor agonist therapy (selexipag) is sometimes pursued. To prevent abrupt withdrawal from parenteral PPA's, overlap transitions are typically used. This report describes 35 inpatient, rapid transitions from parenteral PPA's to oral selexipag. Planned hospital admissions for transition were common (

Indexed as

epoprostenolmedication transitionpulmonary arterial hypertensionselexipagtreprostinil

Identifiers

PMID42598408
PMCPMC13470875

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.