ArticleJournal of Indian Society of Periodontology
Effect of photobiomodulation on diabetic human gingival and periodontal ligament fibroblasts: An
Article in Journal of Indian Society of Periodontology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Aim: This Materials and Methods: DHGF and DPDLF were isolated and harvested from patients with poorly controlled Type 2 diabetes mellitus (HbA1c > 8). The cells were seeded separately in cell-culture plates and exposed to 940 nm diode LASER at 0.1 W power and 2 J or 4 J energy. The cells were exposed once, twice or thrice at 24 h intervals. Cell viability, proliferation, and migration were assessed in test and control groups via Trypan Blue Assay, MTS Assay, and Scratch Test Assay. The experiment was performed in the form of triplicate. Results: Overall, the DHGF and DPDLF, which were exposed to PBM, exhibited better viability, proliferation, and migration than their corresponding controls. Cell viability was significantly higher in DHGF exposed thrice to 4 J energy at 24-h intervals ( Conclusion: PBM using 940 nm diode at 0.1 W power and delivering 2 J energy could be a valuable tool for enhancing periodontal healing in patients with poorly controlled diabetes.
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