Evidence map›Paper›PMID 42598306›Full record

ArticleJournal of pharmacy & bioallied sciences

Pharmacotherapeutic Evaluation of Topical Insulin Versus Medicinal Honey Dressing in the Management of Diabetic Foot Ulcers among Patients with Diabetes Mellitus: A Randomized Controlled Trial.

K Chandramathi, B Tamilarasi, P Padmavathi

Abstract read
In one paragraph

Article in Journal of pharmacy & bioallied sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

K ChandramathiDepartment of Medical Surgical Nursing, Dhanvantri College of Nursing Affiliated to The Tamil Nadu Dr. M. G. R. Medical University, Chennai, Tamil Nadu, India.
B TamilarasiDepartment of Medical Surgical Nursing, Madha College of Nursing, Chennai, Affiliated to The Tamil Nadu Dr. M. G. R. Medical University, Chennai, Tamil Nadu, India.
P PadmavathiDepartment of Obstetrics and Gynaecological Nursing, Dhanvantri College of Nursing Affiliated to The Tamil Nadu Dr. M. G. R. Medical University, Chennai, Tamil Nadu, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Diabetic foot ulcer (DFU) is a serious complication of diabetes mellitus and a major cause of morbidity and lower limb amputation. Effective pharmacological interventions that enhance wound healing are essential for DFU management. Topical insulin has been shown to promote cellular proliferation and angiogenesis, whereas medicinal honey possesses antimicrobial, anti-inflammatory, and tissue regenerative properties. Objective: To compare the effectiveness of topical insulin therapy and medicinal honey dressing in promoting wound healing among patients with DFU. Methods: A randomized controlled superiority trial with a four-group pre-test and post-test design was conducted among 120 patients with Wagner grade I and II DFU. Participants were allocated into four experimental arms ( Results: Both interventions significantly improved wound healing scores ( Conclusion: Both topical insulin and medicinal honey dressing are effective pharmacological adjuncts for DFU management. However, medicinal honey dressing demonstrated superior efficacy in promoting wound healing among patients with diabetes mellitus.

Indexed as

Diabetic foot ulcermedicinal honeypharmacotherapyrandomized controlled trialtopical insulin therapywound healing

Identifiers

PMID42598306
PMCPMC13472555

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.