Evidence map›Paper›PMID 42598301›Full record

ArticleJournal of bone oncology2026

Risk of fracture among lung cancer survivors by cancer treatment modality: A population-based retrospective cohort study.

Seonghye Kim, Kyung-Do Han, Jinhyung Jung, Dong Woog Yoon, Jong Ho Cho, Dong Wook Shin

Abstract read
In one paragraph

Article in Journal of bone oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Seonghye KimDepartment of Family Medicine & Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Kyung-Do HanDepartment of Statistics and Actuarial Science, Soongsil University, Seoul, Republic of Korea.
Jinhyung JungSamsung Biomedical Research Institute, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.
Dong Woog YoonDepartment of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Jong Ho ChoDepartment of Thoracic and Cardiovascular Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.
Dong Wook ShinDepartment of Family Medicine & Supportive Care Center, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Evidence on fracture incidence among lung cancer (LC) survivors remains limited. We assessed fracture risk in LC survivors who underwent curative-intent surgery, stratified by treatment modality and postoperative time. Methods: This retrospective, population-based cohort study used the Korean National Health Insurance Service database (2009-2022), including LC survivors ( Results: LC survivors had an elevated risk of fracture compared with non-cancer controls across the overall follow-up period. Vertebral fracture risk was most pronounced within the first year after surgery (cause-specific hazard ratios [csHRs] 1.81, 95% confidence interval [CI] 1.45-2.26). Hip fracture risk within the first year was similarly directed but did not reach significance in the overall cohort (csHR 1.40, 95% CI 0.98-1.98), whereas it was significantly elevated in the screening subgroup after additional adjustment for health behaviors and body mass index (csHR 1.83, 95% CI 1.11-4.43). During the overall follow-up period, the risk of any fracture was elevated among LC survivors who received chemotherapy (csHR 1.32, 95% CI 1.21-1.45), radiation therapy (csHR 1.78, 95% CI 1.43-2.23), or chemoradiotherapy (csHR 1.73, 95% CI 1.50-1.99), compared with controls. Conclusion: Compared with non-cancer controls, LC survivors had a generally higher risk of fracture at various sites, which varied by time since surgery and by cancer treatment modality. These findings suggest that osteoporosis screening and multimodal fracture prevention strategies should be considered for LC survivors.

Indexed as

Cancer survivorChemoradiotherapyChemotherapyFractureLung cancerRadiation therapy

Identifiers

PMID42598301
PMCPMC13470572

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.