A case of cardiac paraganglioma in a patient with SDHC-related hereditary paraganglioma pheochromocytoma syndrome.

Jaideep Singh Bhalla, Ushasi Saraswati, Agam Bansal, Ossama Abou Hassan, Allan Klein

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Article in European heart journal. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

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5 authors.

Jaideep Singh BhallaDepartment of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.ORCID https://orcid.org/0000-0001-5776-7761

Ushasi SaraswatiDepartment of Internal Medicine, Cleveland Clinic, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

Agam BansalCenter for the Diagnosis and Treatment of Pericardial Diseases, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.

Ossama Abou HassanCenter for the Diagnosis and Treatment of Pericardial Diseases, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.

Allan KleinCenter for the Diagnosis and Treatment of Pericardial Diseases, Department of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.ORCID https://orcid.org/0000-0001-9240-8369

Funding

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6 · The paper itself

Abstract

Background: Cardiac paragangliomas are rare neoplasms, comprising only 1%-3% of primary cardiac tumours, and often pose a diagnostic challenge. Case Summary: A 56-year-old male presented with persistent chest pressure, palpitations and diaphoresis. Cardiac catheterization and further imaging revealed the presence of a fluorodeoxyglucose-avid enhancing epicardial mass accompanied by elevated serum catecholamines. Treatment with doxazosin followed by surgical resection was performed, confirming the diagnosis of cardiac paraganglioma on pathology. Discussion: Whilst rare, cardiac paragangliomas can be hormonally active and symptomatic, necessitating operative management. Accurate differentiation from similar masses on imaging aids in guiding preoperative hormonal evaluations and medical management, as well as in conducting genetic testing to identify causative mutations and assess heritability.

Indexed as

Cardiac tumourCase reportCatecholaminesParaganglioma

Identifiers

PMID42598202

DOI10.1093/ehjcr/ytag375

PMCPMC13472167

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