Evidence map›Paper›PMID 42598199›Full record

ArticleJournal of orthopaedic case reports2026

Back To Basics at The Craniovertebral Junction: Occipito-Cervical Fusion for Basilar Invagination with Atlantoaxial Instability.

Sunil Khemka, Manindra Bhushan, Sandesh Subhash Agrawal, Pritam Agrawal, Ambrish Verma, Ram Khemka

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Article in Journal of orthopaedic case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Sunil KhemkaDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.
Manindra BhushanDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.
Sandesh Subhash AgrawalDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.
Pritam AgrawalDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.
Ambrish VermaDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.
Ram KhemkaDepartment of Orthopedics, Shree Narayana hospital, Raipur, Chhattisgarh, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Basilar invagination (BI) with atlantoaxial instability is a complex craniovertebral junction disorder that causes progressive cervicomedullary compression and disabling myelopathy. Although reduction-based techniques such as distraction-compression-extension-reduction (DCER) have expanded surgical options, conventional occipitocervical fusion remains an important stabilization strategy in selected patients with rigid deformity, advanced neurological compromise, or infective craniovertebral junction pathology. Materials and Methods: This retrospective case series included three patients with BI and atlantoaxial instability, including one with infective C1-C2 spondylodiscitis, who underwent posterior occipitocervical fusion with foramen magnum decompression between 2024 and 2025. Clinical outcomes were assessed using the Nurick grade, Visual Analog Scale (VAS), and Oswestry Disability Index (ODI). Radiographic evaluation included the atlantodental interval (ADI), clivo-axial angle (CXA), Chamberlain's line, and McRae's line. Perioperative complications and neurological outcomes were recorded. All patients completed 12 months of follow-up. Results: All patients presented with advanced myelopathy (Nurick Grade III-V) and marked craniovertebral instability (ADI, 6.2-9.0 mm; CXA, 125°-132°). Posterior occipitocervical fusion with foramen magnum decompression was successfully completed in all patients without intraoperative neurological deterioration, implant-related complications, or revision surgery. Neurological status remained stable or improved throughout follow-up. The patient with infective spondylodiscitis demonstrated improvement in VAS (8 to 3) and ODI (64% to 38%), while all patients achieved radiographic construct stability at final follow-up. Conclusions: Occipitocervical fusion with foramen magnum decompression provided satisfactory neurological stabilization, radiographic stability, and functional improvement in this small series of patients with complex BI and atlantoaxial instability. It remains a valuable stabilization strategy for selected patients when reduction-based techniques are not feasible.

Indexed as

atlantoaxial instabilityBasilar invaginationcervical myelopathyclivo-axial anglecraniovertebral junctionNurick gradeOccipitocervical fusionspondylodiscitis

Identifiers

PMID42598199
PMCPMC13470309

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