Evidence map›Paper›PMID 42598072›Full record

ArticleGynecologic oncology reports2026

Interpreting homologous recombination deficiency in rare gynecological cancers: A case of primary mucinous endometrial adenocarcinoma of gastrointestinal type.

Farhia Kabeer, Dawn Cochrane, Cam Grisdale, Branden J Lynch, Melissa K McConechy, Juliana Sobral de Barros, Lindsay Zibrik, Janine Senz, Amy Jamieson, Jessica N McAlpine and 4 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Gynecologic oncology reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Farhia KabeerDepartment of Basic and Translational Research, BC Cancer Research Institute, Vancouver, BC, Canada.
Dawn CochraneDepartment of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada.
Cam GrisdaleCanada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Branden J LynchDepartment of Basic and Translational Research, BC Cancer Research Institute, Vancouver, BC, Canada.
Melissa K McConechyCanada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Juliana Sobral de BarrosDepartment of Basic and Translational Research, BC Cancer Research Institute, Vancouver, BC, Canada.
Lindsay ZibrikCanada's Michael Smith Genome Sciences Centre, Vancouver, BC, Canada.
Janine SenzDepartment of Basic and Translational Research, BC Cancer Research Institute, Vancouver, BC, Canada.
Amy JamiesonDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Jessica N McAlpineDepartment of Obstetrics and Gynecology, Division of Gynecologic Oncology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Blake GilksDepartment of Pathology and Laboratory Medicine, The University of British Columbia, Vancouver, BC, Canada.
Marco A MarraDepartment of Medical Genetics and the Michael Smith Laboratories, University of British Columbia and BC Cancer Research Institute, Vancouver, BC, Canada.
Janessa LaskinDepartment of Medical Oncology, BC Cancer Centre, Vancouver, BC, Canada.
Yvette DrewDepartment of Medical Oncology, BC Cancer Centre, Vancouver, BC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Mucinous endometrial carcinoma of gastric type (MCG) is a rare and aggressive malignancy with no established standard of care. Biomarkers of homologous recombination deficiency (HRD), including Case presentation: We report a 52-year-old female with metastatic Conclusion: This case demonstrates a discordance between genomic HRD biomarkers and therapeutic response. Despite germline

Indexed as

BRCA1 mutationHomologous recombination deficiencyMucinous endometrial carcinoma of gastric type (MCG)PARPi resistancePrecision oncology

Identifiers

PMID42598072
PMCPMC13471219

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.