ArticleCureus2026
A Case Report of an Unusual Cause of Abnormal Uterine Bleeding: Primary Cervical Lymphoma Misdiagnosed As Hormonal Dysfunction.
Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Primary cervical lymphoma is an exceptionally rare malignancy that may mimic abnormal uterine bleeding (AUB) of endocrine origin, particularly when cervical cancer screening tests and initial imaging studies are normal. Because AUB is the primary manifestation of cervical lymphoma, its diagnosis can be highly challenging. This symptom is frequently shared with prevalent gynecological conditions such as polyps, adenomyosis, leiomyomas, malignancy, and ovulatory dysfunction. When a patient presents with AUB alongside negative screening tests, clinical reasoning is usually directed toward non-structural causes of AUB, delaying the diagnosis of rare lymphoid malignancies that arise deep within the cervical stroma while sparing the superficial epithelium. We present an unusual case of a 44-year-old G2P2 woman with persistent AUB. Initial evaluation, including transvaginal ultrasonography and Papanicolaou testing, was unremarkable, leading to a presumptive diagnosis of ovulatory dysfunction. Given the persistence of symptoms, a follow-up pelvic MRI was performed, revealing an 8.5 x 6.7 x 5.1 cm expansive cervical mass, raising suspicion for advanced squamous cell carcinoma. The diagnosis of primary cervical lymphoma was only confirmed through histopathological and immunohistochemical analysis, which revealed a diffuse large B-cell lymphoma. The proposed treatment consisted of six cycles of chemotherapy according to the R-CHOP protocol (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone). Despite its extreme rarity, primary cervical lymphoma must be included in the differential diagnosis of persistent AUB, especially when conventional cervical cancer screenings and imaging studies are negative. Although many specialists may never encounter this malignancy during their careers, a delayed diagnosis can postpone essential treatment and significantly compromise patient prognosis.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.