Evidence map›Paper›PMID 42597777›Full record

ArticleFrontiers in cell and developmental biology2026

Replicable generation and stable maintenance of rhesus macaque iPSCs for

Julia C Colwell, John P Maufort, Kathryn M Williams, Allison T Makulec, Melissa V Fiorentino, Jeanette M Metzger, Heather A Simmons, Puja Basu, Kerri B Malicki, Celeste M Karch and 3 more

Abstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Julia C ColwellWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
John P MaufortWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Kathryn M WilliamsWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Allison T MakulecWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Melissa V FiorentinoWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Jeanette M MetzgerWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Heather A SimmonsWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Puja BasuWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Kerri B MalickiWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Celeste M KarchDepartment of Psychiatry, Washington University, Saint Louis, MO, United States.
Jacob A MarshDepartment of Psychiatry, Washington University, Saint Louis, MO, United States.
Marina E EmborgWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.
Jenna K SchmidtWisconsin National Primate Research Center, University of Wisconsin-Madison, Madison, WI, United States.

Funding

WNPRC Supplemental Request for Nonhuman Primate Enclosures to Equip HIV/AIDS-Related Research FacilitiesP51OD011106 · OD · UNIVERSITY OF WISCONSIN-MADISON · PI Dorota A. Grejner-Brzezinska · 2012 to 2026
$150.7M
EXTRAMURAL RES FACIL CONST: REPRODUCTIVE, GROWTH &DVMT, MENOPAUSEC06RR020141 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2004 to 2004
$3.6M
A National NHP Embryo Resource of Human Genetic Disease ModelsR24OD034055 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Carol Bailey McCormick Hanna, Larry S. Sherman · 2023 to 2026
$2.7M
Frontotemporal dementia in rhesus macaquesR01NS124857 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI MARINA EMBORG · 2024 to 2026
$2.2M
EXTRAMURAL REGIONAL FACILITIES CONSTRUCTIONC06RR015459 · NCRR · UNIVERSITY OF WISCONSIN MADISON · PI CADWALLADER, MARTIN · 2000 to 2000
$1.9M
Modeling Frontotemporal Dementia in Rhesus MacaquesR33NS115102 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI CHEN, RUI, EMBORG, MARINA · 2022 to 2024
$1.8M
In vitro nonhuman primate model of frontotemporal dementiaF31AG084303 · NIA · UNIVERSITY OF WISCONSIN-MADISON · PI COLWELL, JULIA CLAIRE · 2024 to 2025
$79k
NCRR NIH HHS C06 RR015459NCRR NIH HHS C06 RR020141NIA NIH HHS F31 AG084303NIH HHS P51 OD011106NIH HHS R24 OD034055NINDS NIH HHS R01 NS124857NINDS NIH HHS R33 NS115102
6 · The paper itself

Abstract

At the Wisconsin National Primate Research Center, we have identified a family of rhesus carrying the

Indexed as

frontotemporal dementiainduced pluripotent stem cellMAPT R406Wneural progenitor cellrhesus macaquetautauopathy

Identifiers

PMID42597777
PMCPMC13469415

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.