Evidence map›Paper›PMID 42597598›Full record

ReviewFrontiers in microbiology2026

Liposome drug delivery strategies: state-of-the-art for combating bacterial biofilms.

Tao Lin, Haifeng Liu, Wei He, Wei Hu, Huifang Jiang, Zhiyang Xu, Jintao Wei, Mingdong Yang, Haibin Dai, Junjun Xu

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tao Lin *Department of Ultrasound in Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Haifeng Liu *Department of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wei HeDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Wei HuDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Huifang JiangDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Zhiyang XuDepartment of Infectious Diseases, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Jintao WeiDepartment of Emergency Medicine, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Mingdong YangDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Haibin DaiDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Junjun XuDepartment of Pharmacy, The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial biofilms pose a significant challenge in clinical settings due to their inherent resistance to conventional antibiotics and host immune responses. This review comprehensively discusses the application of liposomal drug delivery systems as a cutting-edge strategy to combat biofilm-associated infections. It begins by outlining the biological characteristics of biofilms, including their formation process and the protective extracellular polymeric substance (EPS) matrix. The manuscript then focuses on the advantages of liposomes, such as their nanoscale size effect, modifiable surface properties, and sustained-release capabilities, which enhance penetration through the EPS and improve drug accumulation at infection sites. Furthermore, it details species-specific strategies against pathogens like

Indexed as

anti-infection therapybacterial bioflimsbioflim barrierdrug delivery systemsliposome

Identifiers

PMID42597598
PMCPMC13469010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.