Evidence map›Paper›PMID 42597557›Full record

ArticleAdvanced fiber materials2026

A Dual-Crosslinked Metallo-elastomer Platform for Architecture-Directed Vascular Remodeling.

Narangerel Gantumur, Shuhao Jiao, Xiaochu Ding, Simon Van Herck, Isabella Frangiosa, Emily Kopchick, Caitlin Maureen Purdy, Ty Walker, Aarati Kharal, Ying Grace Chen

Abstract read
In one paragraph

Article in Advanced fiber materials, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Narangerel Gantumur *Department of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Shuhao Jiao *Department of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Xiaochu DingHealth Research Institute, Michigan Technological University, H-STEM 238, 1400 Townsend Drive, Houghton, MI 49931 USA.
Simon Van HerckDepartment of Instructive Biomaterials Engineering, MERLN Institute for Technology-Inspired Regenerative Medicine, Maastricht University, Universiteitssingel 40, 6229 ER Maastricht, The Netherlands.
Isabella FrangiosaDepartment of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Emily KopchickDepartment of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Caitlin Maureen PurdyCenter for Research and Education in Advanced Transportation Engineering Systems (CREATES) of the Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Ty WalkerDepartment of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Aarati KharalDepartment of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.
Ying Grace ChenDepartment of Biomedical Engineering, Henry M. Rowan College of Engineering, Rowan University, 201 Mullica Hill Road, Glassboro, NJ 08028 USA.ORCID 0000-0002-0333-2217

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The engineering of durable small-diameter vascular grafts remains constrained by the challenge of simultaneously achieving mechanical robustness, controlled degradation, and instructive scaffold architecture. Here, we report a programmable dual-crosslinked metallo-elastomer platform, poly(1,3-propylene itaconate-co-2,2'-bipyridine-5,5'-dicarboxylate-co-succinate-co-sebacate) (M-PBIS), that integrates dynamic metal-ligand coordination with covalent crosslinking to enable orthogonal control over network mechanics, time-dependent viscoelastic behavior, and processability. PBIS polymers were synthesized by modular step-growth polyesterification, allowing independent tuning of backbone composition, bipyridine ligand density for metal coordination, and alkene (C = C) content for covalent crosslinking. This multidimensional design space allowed systematic tuning of tensile elastic modulus (0.06-3.2 MPa), extensibility (53%-491%), toughness (66-1339 kJ m Graphical abstract: Supplementary Information: The online version contains supplementary material available at 10.1007/s42765-026-00744-9.

Indexed as

Circumferentially-biased helically wound fiber alignmentDual-crosslinked metallo-elastomersElectrowritingIn situ vascular remodelingResorbable vascular graft

Identifiers

PMID42597557
PMCPMC13468867

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.