Evidence map›Paper›PMID 42597343›Full record

ReviewFrontiers in medicine2026

R-(+)-propranolol for infantile hemangioma:

Wei Peng, Feng Chen, Yuyang Zheng, Yong Zeng, Zhiqi Zhao, Qian Liu, Haijin Liu

Abstract readReview
In one paragraph

Review in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Wei Peng *Department of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Feng Chen *Department of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Yuyang Zheng *The First Clinical Medical College of Gannan Medical University, Ganzhou, China.
Yong ZengDepartment of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Zhiqi ZhaoThe First Clinical Medical College of Gannan Medical University, Ganzhou, China.
Qian LiuDepartment of Clinical Research Center of Vascular Abnormalities of Jiangxi Province, Ganzhou, China.
Haijin LiuDepartment of Pediatric Surgery, First Affiliated Hospital of Gannan Medical University, Ganzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infantile hemangioma (IH) is the most prevalent benign vascular tumor in infancy, and propranolol is the first-line standard pharmacotherapy for high-risk IH. The clinically used formulation of propranolol is an equimolar 1:1 racemic mixture of two enantiomers, S-(-)-propranolol and R-(+)-propranolol. The traditional mechanistic hypothesis is centered on the

Indexed as

angiogenesischiral druginfantile hemangiomaR-(+)-propranololSOX18β-adrenoceptor-independent mechanism

Identifiers

PMID42597343
PMCPMC13467852

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.