Evidence map›Paper›PMID 42597319›Full record

ReviewFrontiers in microbiology2026

Insights into the mechanisms of infection transmission via inanimate surfaces.

Katia Iskandar, Loïc Marchin, Christine Roques

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Katia IskandarFaculty of Public Health-Section 2, Lebanese University, Fanar, Lebanon.
Loïc MarchinPylote SAS, Drémil-Lafage, Toulouse, France.
Christine RoquesLaboratoire de Génie Chimique, CNRS, INPT, UPS, Faculté de Pharmacie, Université de Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Inanimate surfaces are critical reservoirs for pathogenic microorganisms, increasing the risk of infectious disease transmission across healthcare, household, and public settings. This comprehensive review synthesizes current evidence on microbial contamination mechanisms, examining the complex interplay between pathogen characteristics, surface properties, and environmental conditions that govern fomite-mediated transmission. Contamination sources are diverse, originating from human shedding, respiratory secretions, environmental reservoirs, including airborne particles and water drainage systems, as well as contaminated materials such as medications, medical devices, and personal items. Pathogen persistence on surfaces ranges from hours to months, influenced by microorganism-specific attributes such as biofilm formation capacity, spore production, and structural characteristics that distinguish bacterial, viral, and fungal species. Environmental parameters, including temperature, relative humidity, pH, and light exposure, influence patterns of survival. Moisture-rich environments, in particular, enable persistence of Gram-negative bacteria and biofilm development. Surface characteristics, notably porosity, roughness, and material composition, create distinct microenvironments affecting microbial adhesion and persistence. Non-porous surfaces such as stainless steel and plastic generally support extended bacterial viability, whereas porous materials exhibit complex, pathogen-dependent survival patterns. Evidence from experimental studies, epidemiological investigations, and mathematical modeling confirms that inanimate surfaces are significant transmission vectors, particularly in healthcare settings where they contribute to 20-40% of healthcare-associated infections. Critical knowledge gaps persist regarding viable but non-culturable organisms, real-world transmission dynamics, and optimal cleaning/disinfection strategies. Future research priorities include developing advanced detection methods, refining cleaning and disinfection protocols, validating antimicrobial surface technologies, and establishing predictive models of transmission.

Indexed as

biofilmscolonizationenvironmental reservoirsfomiteshealthcare-associated infectionsinfectious riskmicrobial contaminationsurface contamination

Identifiers

PMID42597319
PMCPMC13468806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.