ArticleFrontiers in medicine2026
Intravascular ultrasound analysis of spontaneous pulmonary artery lumen enlargement after balloon pulmonary angioplasty in patients with chronic thromboembolic pulmonary hypertension.
Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Balloon pulmonary angioplasty (BPA) is an important therapeutic strategy for chronic thromboembolic pulmonary hypertension (CTEPH) requiring staged procedures. Notably, incompletely expanded pulmonary artery lumens enlarge spontaneously between sessions, but the mechanism remains unclear. Objectives: To investigate the morphological mechanisms of spontaneous lumen enlargement after BPA and their association with vasoactive mediators. Methods: A total of 151 pulmonary artery segments from 92 BPA procedures in 24 CTEPH patients were included for analysis. Intravascular ultrasound (IVUS) was used to assess the same vascular segments immediately after the first BPA procedure and again before the second BPA procedure. Plasma levels of vasoactive mediators were also measured in the corresponding pulmonary artery segments at both time points. Results: Before the second procedure, IVUS showed significant increases in lumen area (LA, 10.2 → 16.8 mm Conclusion: Spontaneous lumen enlargement after BPA was associated with vascular enlargement and reduced lesion burden, suggesting a morphological basis for this phenomenon. Pulmonary vascular enlargement may be associated with increased plasma NOx levels.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.