ArticleAmerican journal of cancer research2026
Effects of oliceridine-based patient-controlled intravenous administration on postoperative pain and hemodynamic stability in elderly patients undergoing laparoscopic surgery for colorectal cancer.
Article in American journal of cancer research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
The dose-effect relationship and hemodynamic effects of oliceridine in elderly patients undergoing laparoscopic surgery remain unclear. This study evaluated the effects of different doses of oliceridine administered via patient-controlled intravenous analgesia (PCIA) on postoperative pain management in older adults with colorectal cancer. Patients were divided into three groups according to the analgesic regimen: a control group (Group C, fentanyl PCIA), a low-dose oliceridine group (Group O1), and a high-dose oliceridine group (Group O2), each comprising 50 patients. Outcomes included resting and movement numeric rating scale (NRS) scores, incidence of moderate-to-severe pain, Ramsay sedation scores, Quality of Recovery-15 (QoR-15) scores, patient satisfaction, inflammatory cytokine levels, hemodynamic and respiratory parameters, and adverse reactions. The total opioid load was similar across the three groups. Group O2 showed consistently lower resting and movement NRS scores at all observation time points (all
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