Evidence map›Paper›PMID 42597259›Full record

ArticleTransplant international : official journal of the European Society for Organ Transplantation2026

Assessing and cataloguing cognitive impairment in older potential kidney transplant patients: key recommendations from the ethical and legal issues working group of ELPAT.

J A Holland, J S L Partridge, R L Thom, I Raburn, D M Summers, A Ruck Keene, E M Bunnik, A J Cronin

Abstract readConsensus Statement
In one paragraph

Article in Transplant international : official journal of the European Society for Organ Transplantation, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

J A HollandDepartment of Transplant Surgery, Renal Medicine, and Urology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
J S L PartridgeDepartment of Perioperative Medicine for Older People Undergoing Surgery, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
R L ThomDepartment of Renal Medicine, Royal London Hospital, Barts NHS Foundation Trust, London, United Kingdom.
I RaburnDepartment of Philosophy, King's College London, London, United Kingdom.
D M SummersDepartment of Transplant Surgery, Cambridge University Hospital NHS Foundation Trust, Cambridge, United Kingdom.
A Ruck KeeneDickson Poon School of Law, King's College London, London, United Kingdom.
E M BunnikDepartment of Public Health, Medical Ethics, Philosophy and History of Medicine Programme, Erasmus University Medical Centre, Rotterdam, Netherlands.
A J CroninDepartment of Transplant Surgery, Renal Medicine, and Urology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cognitive impairment is common in older patients with advanced kidney disease and may influence access to and outcomes from kidney transplantation. However, its assessment and documentation within transplant evaluation remain inconsistent, with important ethical and legal implications. This position paper from the Ethical and Legal Issues Working Group of ELPAT synthesises current evidence, ethical and legal frameworks, and findings from a UK-wide national survey to propose a structured approach to the assessment and documentation of cognitive impairment in older potential kidney transplant recipients. Survey data demonstrate substantial variability in screening practices, documentation, and capacity assessment during transplant workup, contrasting with the standardised evaluation of other transplant domains. Cognitive impairment may affect decision-making capacity, perioperative risk, post-transplant self-management, and graft outcomes, raising important ethical considerations regarding autonomy, equity, and resource allocation. We recommend routine screening using validated tools, standardised documentation within clinical records and registries, use of these data to inform policy and research, prioritisation of cognitive outcomes in future studies, and targeted education and training in cognitive and capacity assessment. Embedding these measures within transplant pathways will support equitable access, informed decision-making, and improved outcomes.

Indexed as

Cognitive DysfunctionKidney TransplantationAgedCognition DisordersDecision MakingHumansUnited Kingdomcognitioncognition dysfunctionequity in transplantationethical aspects of organ transplantation and donationtransplant

Identifiers

PMID42597259
PMCPMC13468520

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