Observational studyFrontiers in neurology2026
Mediation of the relationship between cerebral blood flow and functional outcomes by quantification of perforator collateral capacity in patients with minor stroke and large vessel occlusion.
Observational study in Frontiers in neurology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Recognition of lenticulostriate arteries (LSAs) may reflect the presence of beneficial local collaterals. This study determined whether the morphological characteristics of LSAs were associated with clinical outcomes in individuals with intracranial atherosclerosis-related large vessel occlusion (ICAS-LVO) and minor stroke who underwent endovascular treatment and examined the potential hemodynamic relevance of these features. Materials and methods: This retrospective observational study included consecutive individuals with ICAS-LVO and minor stroke who underwent successful endovascular treatment between June 2020 and March 2022. LSA morphology was assessed on preinterventional high-resolution magnetic resonance imaging (HR-MRI) and classified as relatively good (LSA-sign+) or reduced (LSA-sign-). Cerebral blood flow in the LSA territory was quantified using arterial spin labeling. Associations between LSA characteristics, cerebral blood flow, and clinical outcomes were evaluated using multivariable logistic regression and Spearman correlation analyses, adjusted for potential confounders. Results: Of 52 individuals included (median age, 59 years; 40 men), 24 (46.2%) had LSA-sign+. Multivariable analysis revealed that longer total LSA length was independently associated with higher odds of favorable outcome at 90 days (modified Rankin Scale score ≤2; OR = 1.14; 95% CI, 1.02-1.27; Conclusion: Total LSA length on preinterventional HR-MRI was an independent predictor of favorable outcomes after endovascular treatment. These findings provide new insight that may support clinical decision-making in ICAS-LVO and minor stroke.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.