ArticlePregnancy (Hoboken, N.J.)2025
Effect of continuous positive airway pressure on umbilical artery pH during scheduled cesarean delivery in individuals with class III obesity: A randomized controlled trial.
Article in Pregnancy (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04993651 (Effect of Continuous Positive Airway Pressure on Fetal pH at Time of Scheduled Cesarean Delivery in Morbidly Obese Women), which is not on this map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Effect of Continuous Positive Airway Pressure on Fetal pH at Time of Scheduled Cesarean Delivery in Morbidly Obese Women
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Objective: To evaluate the effect of continuous positive airway pressure (CPAP) on umbilical artery pH when utilized intraoperatively during scheduled cesarean delivery in individuals with class III obesity, defined as a body mass index (BMI) ≥ 40 kg/m Study design: This was a randomized controlled study of individuals with class III obesity and singleton pregnancy who underwent scheduled cesarean delivery. Subjects were randomized to receive the institutional standard of care consisting of oxygen 2 liters per minute (L/min) via nasal cannula or CPAP containing oxygen supplementation of 2 L/min during cesarean delivery. The primary outcome was umbilical artery pH. Secondary outcomes included umbilical venous blood gas values, maternal venous blood gas values, neonatal and maternal outcomes, intraoperative parameters, and maternal satisfaction. Results: Of 65 subjects, 33 were randomized to CPAP and 32 to oxygen 2 L/min via nasal cannula. A total of 12 participants in the CPAP group were unable to tolerate the device for the planned duration and subsequently received 2 L/min of oxygen via nasal cannula. Modified intention to treat analysis showed no difference in the mean umbilical arterial pH between the CPAP and routine management groups (7.18 vs. 7.19; Conclusion: Compared to routine oxygen supplementation, CPAP was not associated with improved umbilical artery pH in individuals with class III obesity undergoing scheduled cesarean delivery. Trial Registration: ClinicalTrials.gov Identifier: NCT04993651.
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