Evidence map›Paper›PMID 42597062›Full record

ArticlePregnancy (Hoboken, N.J.)2025

Intersectionality of individual and neighborhood-level adverse social determinants of health in early pregnancy.

Jameaka L Hamilton, William A Grobman, Jiqiang Wu, Lynn M Yee, David Haas, Becky Mcneil, Brian Mercer, Hyagriv Simhan, Uma Reddy, Robert M Silver and 5 more

Abstract read
In one paragraph

Article in Pregnancy (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Jameaka L HamiltonDepartment of Obstetrics and Gynecology The Ohio State University Columbus Ohio USA.
William A GrobmanDepartment of Obstetrics and Gynecology The Ohio State University Columbus Ohio USA.
Jiqiang WuDepartment of Obstetrics and Gynecology The Ohio State University Columbus Ohio USA.
Lynn M YeeDepartment of Obstetrics and Gynecology Northwestern University Chicago Illinois USA.
David HaasDepartment of Internal Medicine The Ohio State University Columbus Ohio USA.
Becky McneilRTI International Durham North Carolina USA.
Brian MercerDepartment of Obstetrics and Gynecology Case Western Reserve University Cleveland Ohio USA.
Hyagriv SimhanDepartment of Obstetrics and Gynecology University of Pittsburgh Pittsburgh Pennsylvania USA.
Uma ReddyDepartment of Obstetrics and Gynecology Columbia University New York New York USA.
Robert M SilverDepartment of Obstetrics and Gynecology University of Utah Salt Lake City Utah USA.
Samuel ParryDepartment of Obstetrics and Gynecology University of Pennsylvania Philadelphia Pennsylvania USA.
George SaadeDepartment of Obstetrics and Gynecology University of Texas Medical Branch Galveston Texas USA.
Jun WuDepartment of Environmental and Occupational Health University of California, Irvine Orange California USA.
Courtney D LynchDepartment of Obstetrics and Gynecology The Ohio State University Columbus Ohio USA.
Kartik K VenkateshDepartment of Obstetrics and Gynecology The Ohio State University Columbus Ohio USA.

Funding

Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063036 · NICHD · RESEARCH TRIANGLE INSTITUTE · PI PARKER, CORETTE BREEDEN · 2010 to 2015
$19.5M
Institute for Clinical and Translational ScienceUL1TR000153 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M · 2012 to 2015
$12.1M
Prevention of Preterm Birth in high Risk Nulliparous PatientsU10HD063047 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI WAPNER, RONALD · 2010 to 2014
$1.9M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063053 · NICHD · UNIVERSITY OF UTAH · PI SILVER, ROBERT M. · 2010 to 2014
$1.7M
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk U10HD063020 · NICHD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI GROBMAN, WILLIAM ADAM · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063046 · NICHD · UNIVERSITY OF CALIFORNIA-IRVINE · PI WING, DEBORAH A · 2010 to 2014
$1.6M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063041 · NICHD · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI SIMHAN, HYAGRIV N · 2010 to 2014
$1.5M
Preterm Birth in Nulliparous Women: An Understudied Population at Great RiskU10HD063048 · NICHD · UNIVERSITY OF PENNSYLVANIA · PI PARRY, SAMUEL I. · 2010 to 2014
$1.5M
Dissecting the Genetic Etiology of Preterm Birth in Nulliparous WomenU10HD063037 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI HAAS, DAVID M. · 2010 to 2014
$1.2M
Adverse Outcomes in Nulliparous Pregnancies: The Ohio CollaborativeU10HD063072 · NICHD · CASE WESTERN RESERVE UNIVERSITY · PI MERCER, BRIAN M. · 2010 to 2014
$1.2M
NCATS NIH HHS UL1 TR000153NCATS NIH HHS UL1 TR001108NICHD NIH HHS U10 HD063020NICHD NIH HHS U10 HD063036NICHD NIH HHS U10 HD063037NICHD NIH HHS U10 HD063041NICHD NIH HHS U10 HD063046NICHD NIH HHS U10 HD063047NICHD NIH HHS U10 HD063048NICHD NIH HHS U10 HD063053NICHD NIH HHS U10 HD063072
6 · The paper itself

Abstract

Introduction: Individual- and neighborhood-level social determinants of health (SDOH) have been assessed separately in pregnancy, but their relationship to one another remains uncertain. We investigated the intersectionality of three neighborhood-level SDOH measures with three individual-level SDOH measures. This was done to examine the concomitant experiences of multiple SDOH in pregnancy. Methods: A secondary analysis of data from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-To-Be. We assessed three neighborhood-level SDOH measures using geocoded participant home addresses in the first trimester at the census-tract level: (1) high socioeconomic disadvantage (in tertiles) by the 2015 Area Deprivation Index, (2) inadequate food access by the USDA Results: Of 9588 nulliparous individuals, adverse neighborhood-level SDOH [high socioeconomic disadvantage (28%), inadequate food access (24%), and low walkability (66%)] and adverse individual-level SDOH [low household income (19%), lower educational attainment (23%), and Medicaid insurance (33%)] were common in early pregnancy. Six percent of individuals lived in a community with all three adverse neighborhood-level SDOH measures. Of those living in a community with at least two neighborhood-level SDOH measures, 23% lived in areas with inadequate food access and low walkability, 19% with high socioeconomic disadvantage and low walkability, and 1% with high socioeconomic disadvantage and inadequate food access. Overall, 23% lived in a community with no adverse neighborhood-level SDOH, and among this group, 88% had no adverse individual-level SDOH. There were significant differences in adverse individual-level SDOH based on whether individuals lived in a community with all three adverse neighborhood-level measures [low household income (39%), lower educational attainment (44%), Medicaid (55%)], any two measures [low household income (22%), lower educational attainment (27%), Medicaid (37%)], or only one measure [low household income (14%), lower educational attainment (17%), Medicaid (27%)] ( Conclusion: Among nulliparous individuals in early pregnancy, the frequency of adverse individual-level SDOH was generally higher when they lived in communities with more adverse neighborhood-level SDOH. Future approaches that identify and classify the multifaceted and multilevel nature of structural determinants as they relate to pregnancy outcomes are needed.

Indexed as

individualneighborhoodpregnancysocial determinants of health

Identifiers

PMID42597062
PMCPMC13344772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.