ArticlePregnancy (Hoboken, N.J.)2025
Mood disorders and peripartum cardiomyopathy.
Article in Pregnancy (Hoboken, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Objective: To examine the association between mood disorders and peripartum cardiomyopathy (PPCM). Methods: Retrospective cohort study utilizing the National Inpatient Sample from the Healthcare Cost and Utilization Project, Agency for Healthcare Research and Quality of pregnant and postpartum patients from 2017 to 2019. Patients were separated into two groups based on ICD-10 coding for the presence or absence of mood disorder (depression, bipolar depression, anxiety, or other mood diagnosis). The primary outcome was diagnosis of PPCM. Secondary outcomes included a composite of adverse cardiac events and maternal death. Groups were compared via Results: Over 2.2 million subjects were analyzed and approximately 168,000 (7.3%) had an ICD-10 diagnosis of mood disorder. Those with mood disorders were more likely to be non-Hispanic white, obese, tobacco users, publicly insured, have comorbidities, and deliver at a large, private, non-profit hospital (all Conclusion: Mood disorders in pregnancy and postpartum are associated with increased rates of PPCM and other cardiac events.
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