Evidence map›Paper›PMID 42596593›Full record

ArticleScandinavian journal of primary health care2026

Out-of-hours C-reactive protein point-of-care testing and its association with long-term healthcare-seeking.

Jesper Lykkegaard, Jonas K Olsen, Claus Høstrup Vestergaard, Malene Plejdrup Hansen, Linda Huibers

Abstract read
In one paragraph

Article in Scandinavian journal of primary health care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jesper LykkegaardResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Denmark.ORCID 0000-0001-9128-6136
Jonas K OlsenResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Denmark.ORCID 0000-0001-7286-2513
Claus Høstrup VestergaardResearch Unit for General Practice, Aarhus, Denmark.ORCID 0000-0003-2916-1548
Malene Plejdrup HansenResearch Unit of General Practice, Department of Public Health, University of Southern Denmark, Denmark.ORCID 0000-0002-8444-1369
Linda HuibersResearch Unit for General Practice, Aarhus, Denmark.ORCID 0000-0002-5048-3026

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased diagnostic testing may contribute to clinically unnecessary healthcare-seeking.

aimTo analyse whether patients exposed to general practitioners (GPs) who frequently use C-reactive protein point-of-care testing (CRP-POCT) have different long-term use of out-of-hours (OOH) primary care services. DESIGN AND

settingRegister-based time-to-event analysis of OOH primary care in the Central Denmark Region (population 1.3 million). The service functions as gatekeeper to hospital care. The GPs work a limited number of shifts per month.

methodsAll in-person clinic consultations at the OOH clinics from 2014 to 2017 were included. The exposure was the consulted GP's adjusted tendency to perform CRP-POCT relative to peer GPs, based on the latest 50 consultations. Covariates included patient characteristics, GP activity level and experience in OOH care, and time of consultation. Hazard ratios (HRs) for revisiting OOH primary care were estimated.

resultsA total of 862,733 consultations were included. The proportion of consultations involving CRP-POCT increased from 12% in 2014 to 19% in 2017. Kaplan-Meier estimates showed that it took 2.5 years before half of the patients had returned for an OOH consultation. The adjusted HR for revisiting was 1.038 (95% CI = 1.023 to 1.054) for patients seen by a GP with twice the average CRP-POCT use or higher, compared with those seen by a GP with average use.

conclusionBeing seen by a GP with a high propensity to use CRP-POCT was associated with increased long-term OOH all-cause healthcare-seeking. This may reflect effects of CRP-POCT itself, correlated GP characteristics, or both.

Indexed as

After-Hours CareC-Reactive ProteinPatient Acceptance of Health CarePoint-of-Care TestingPrimary Health CareAdolescentAdultAgedChildChild, PreschoolDenmarkFemaleGeneral PractitionersHumansMaleMiddle AgedC-Reactive Proteinafter-hours careC-reactive proteinhealth services utilizationPoint-of-care testingprimary health care

Identifiers

PMID42596593
PMCPMC13479521

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.