Evidence map›Paper›PMID 42596066›Full record

ArticleMagnetic resonance in medicine2026

p-Brain: A Modular Open-Source Framework for Automated Quantitative DCE-MRI of Cerebral Perfusion, Microvasculature, and Blood-Brain Barrier Permeability.

Edis D Tireli, Stig P Cramer, Ulrich Lindberg, Derya Tireli, Mark B Vestergaard, Henrik B W Larsson

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Magnetic resonance in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Edis D TireliFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.ORCID https://orcid.org/0009-0009-3585-4333
Stig P CramerFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Ulrich LindbergFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Derya TireliFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Mark B VestergaardFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.
Henrik B W LarssonFunctional Imaging Unit, Department of Clinical Physiology and Nuclear Medicine, Copenhagen University Hospital, Rigshospitalet, Glostrup, Denmark.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present p-Brain, a modular, open-source framework for reproducible, automated quantitative DCE-MRI at scale. Rather than a fixed pipeline, p-Brain is built from interchangeable stages (ingestion,

Indexed as

Blood-Brain BarrierBrainCerebrovascular CirculationImage Processing, Computer-AssistedMicrovesselsAlgorithmsContrast MediaConvolutional Neural NetworksDynamic Contrast Enhanced Magnetic Resonance ImagingHumansPerfusion Magnetic Resonance ImagingReproducibility of ResultsSoftwareContrast Mediaautomationblood–brain barrierdynamic contrast‐enhanced MRIperfusionpermeability

Identifiers

PMID42596066
PMCPMC13619889

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.