Evidence map›Paper›PMID 42595777›Full record

ArticleScientific reports2026

Amelioration of cadmium toxicity in Vicia faba via modulation of caffeic acid O-methyltransferase gene expression by biochar and nanobiochar.

Sherifa F M Dawoud, Medhat Rehan, Fatmah Ahmed Safhi, Esraa M A El-Shazly, Nora M Al Aboud, Noha A Sukar, Amany A El Sadawy, Safaa A El-Shazly, Abdelrahman A Awad, Mohamed Elzarei and 1 more

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Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sherifa F M DawoudAgriculture Faculty (Girls branch), Al-Azhar University, Cairo, 11884, Egypt.
Medhat RehanDepartment of Plant Production, College of Agriculture and Food, Qassim University, Buraydah, 51452, Saudi Arabia.
Fatmah Ahmed SafhiDepartment of Biology, College of Science, Princess Nourah bint Abdulrahman University, P.O. Box 84428, Riyadh, 11671, Saudi Arabia.
Esraa M A El-ShazlyDepartment of Agricultural Botany, Faculty of Agriculture, Tanta University, Tanta, Egypt.
Nora M Al AboudDepartment of Biology, College of Science, Umm Al-Qura University, Makkah, Saudi Arabia.
Noha A SukarAgricultural Botany Department, Faculty of Agriculture, (Girls branch), Al-Azhar University, Cairo, Egypt.
Amany A El SadawyAgriculture Faculty (Girls branch), Al-Azhar University, Cairo, 11884, Egypt.
Safaa A El-ShazlyAgriculture Faculty (Girls branch), Al-Azhar University, Cairo, 11884, Egypt.
Abdelrahman A AwadAgricultural Botany, (Genetics) Department, Faculty of Agriculture, Al-Azhar University, Cairo, Egypt.
Mohamed ElzareiDepartment of Animal and Poultry Production, College of Agriculture and Food, Qassim University, Buraydah, 51452, Saudi Arabia.
Amina M G ZedanAgriculture Faculty (Girls branch), Al-Azhar University, Cairo, 11884, Egypt. Aminazedan1948.el@azhar.edu.eg.

Funding

Princess Nourah bint Abdulrahman University with a number (PNURSP2025R318) (PNURSP2025R318)
6 · The paper itself

Abstract

Cadmium (Cd) is considered one of the most mobile and toxic environmental contaminant on all organisms. This study aimed to remove the toxicity effect of Cd with important natural materials without harmful side effect on the living organisms. Two concentrations (1% and 2%) of biochar and nano-biochar (with an average particle size of 15.13 nm) were applied to Vicia faba L. under Cd stress (200 µM) by adding them to Hoagland's nutrition solution. Results indicated that Cd significantly decreased plant growth parameters (root and shoot length, fresh and dry weights of shoot and root and leaf area) and chlorophyll levels under Cd stress. Cd elevated the antioxidant enzymes and proline levels. The genes that are engaged in the melatonin pathway (N-acetylserotonin, methyltransferase, Serotonin N-acetyltransferase slightly interacted (if any) with Cd stress. Caffeic acid O-methyltransferase (COMT) only showed a significant response to Cd, with a 3.74-fold increase in expression at the first time-point. At the same time, biochar and nano-biochar effectively reduced the harmful effects of Cd on plant growth, improved physiological responses, and modulated the expression of the COMT gene. Nano-biochar exhibited particularly strong improvements across various growth parameters. This is the first time studying these genes in Vicia faba plants under any stress. COMT is involved in other pathways such as lignin pathway and might be expressed in response to Cd stress as a part of this pathway.

Indexed as

CadmiumCharcoalGene Expression Regulation, PlantMethyltransferasesVicia fabaChlorophyllPlant ProteinsPlant RootsbiocharCadmiumcaffeate O-methyltransferaseCharcoalChlorophyllMethyltransferasesPlant ProteinsCaffeic acid O-methyltransferase, gene expressionCd stressMelatonin pathwayNano-biochar

Identifiers

PMID42595777
PMCPMC13473552

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.