Evidence map›Paper›PMID 42595701›Full record

ArticleInternational journal of qualitative studies on health and well-being2026

"It's taken away the most fundamental things about being human": the lived experience and impact of post-SSRI sexual dysfunction.

Seraj Brugi, Bob Budd, Craig Mackie, Sarah Fish

Abstract read
In one paragraph

Article in International journal of qualitative studies on health and well-being, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Seraj BrugiDepartment of Clinical Psychology and Psychological Therapies, University of East Anglia, Norwich, United Kingdom.ORCID 0009-0000-7247-3462
Bob BuddDepartment of Clinical Psychology and Psychological Therapies, University of East Anglia, Norwich, United Kingdom.
Craig MackieNorfolk and Suffolk NHS Foundation Trust, Norfolk, United Kingdom.
Sarah FishDepartment of Clinical Psychology and Psychological Therapies, University of East Anglia, Norwich, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt has become increasingly recognized that sexual side effects from serotonergic antidepressants can last long after the medication has been discontinued, but little is known about the lived experience of post-SSRI sexual dysfunction (PSSD) and its impact on people's identities, relationships, and mental health. This qualitative study aimed to understand the experiences of people living with PSSD in the United Kingdom.

methodsTen participants were invited to take part in a semi-structured interview, and the data were analysed using an interpretive phenomenological approach.

resultsThree themes, encompassing eight subthemes, were identified: (1) distrustful of professionals; (2) a changed me; and (3) living with the impact. The participants discussed their experiences of being dismissed and unheard, feeling emotionally numb, and making sense of the change and losses they have experienced. Implications for clinical practice include the importance of professionals being aware of PSSD and its potential impact.

conclusionsPSSD can affect every aspect of daily life, impacting more than just individuals' sexual functioning and satisfaction. Further research is needed on effective treatments, including psychological interventions, which can offer meaningful support.

Indexed as

Selective Serotonin Reuptake InhibitorsSexual Dysfunction, PhysiologicalSexual Dysfunctions, PsychologicalAdultFemaleHumansMaleMiddle AgedQualitative ResearchTrustUnited KingdomSelective Serotonin Reuptake Inhibitorslived experiencePost-SSRI sexual dysfunctionPSSDselective serotonin reuptake inhibitorssexual side effectsSSRIs

Identifiers

PMID42595701
PMCPMC13474523

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.