Evidence map›Paper›PMID 42595340›Full record

ArticleBone & joint research2026

A novel diagnostic technology rapidly detects the presence of infection and defines antimicrobial sensitivities in organisms typical for joint infection.

Isabelle L Cochrane, Roselline Gabriella Gunarto, Frank Alexander Schildberg, Dieter Christian Wirtz, Robert J H Hammond, Phillip J Walmsley

Abstract read
In one paragraph

Article in Bone & joint research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Isabelle L CochraneSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0009-0003-2147-7721
Roselline Gabriella GunartoSchool of Medicine, University of St Andrews, St Andrews, UK.
Frank Alexander SchildbergDepartment of Orthopaedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.ORCID 0000-0003-0797-1945
Dieter Christian WirtzDepartment of Orthopaedics and Trauma Surgery, University Hospital Bonn, Bonn, Germany.ORCID 0000-0002-6189-5114
Robert J H HammondSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0003-3664-3641
Phillip J WalmsleySchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0002-7515-7243

Funding

German Research FoundationJohn Templeton FoundationUniversity of St Andrews
6 · The paper itself

Abstract

Aims: Infective arthritis is rare, but serious. Timely treatment with appropriate antimicrobial therapy is potentially life- and limb-saving, but our ability to deliver this is limited by current laboratory practices, which confer a delay of several days before antimicrobial sensitivities are available. We propose a novel diagnostic modality, the Scattered Light Integrating Collector (SLIC), which monitors bacterial growth in real time, allowing a diagnosis of infection to be made in minutes, and antimicrobial sensitivities to be delivered in under an hour. Methods: We collated data previously collected on SLIC relating to laboratory strains of Results: TTP for Conclusion: SLIC rapidly determines the presence of infection and characterizes antimicrobial susceptibilities in organisms typical for joint infection.

Identifiers

PMID42595340
PMCPMC13472738

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.