Evidence map›Paper›PMID 42595207›Full record

ArticleCellular and molecular gastroenterology and hepatology2026

Intact Cell Dissociation of Formalin-Fixed Paraffin-Embedded Colon Tissue Enhances Cell Recovery and Gene Detection in Single-Cell RNA Sequencing.

James R Evans, Alan J Simmons, Zhengyi Chen, Monica E Brown, Matthew E Bechard, Morad C Malek, Cody N Heiser, Frank Revetta, M Kay Washington, Laura P Hale and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cellular and molecular gastroenterology and hepatology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

James R EvansEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Program in Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee.
Alan J SimmonsEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee.
Zhengyi ChenEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Program in Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee.
Monica E BrownEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee.
Matthew E BechardEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee.
Morad C MalekDepartment of Biochemistry, Vanderbilt University, Nashville, Tennessee.
Cody N HeiserEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Program in Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee.
Frank RevettaDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
M Kay WashingtonDepartment of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, Tennessee.
Laura P HaleDepartment of Pathology, Duke University Medical Center, Durham, North Carolina; Human Vaccine Institute, Duke University Medical Center, Durham, North Carolina.
Robert J CoffeyEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee; Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee.
Ken S LauEpithelial Biology Center, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Computational Systems Biology, Vanderbilt University, Nashville, Tennessee; Program in Chemical and Physical Biology, Vanderbilt University, Nashville, Tennessee; Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee; Vanderbilt-Ingram Cancer Center, Nashville, Tennessee; Vanderbilt Institute for Infection, Immunology, and Inflammation, Vanderbilt University Medical Center, Nashville, Tennessee; Center for Mucosal Inflammation and Cancer, Vanderbilt University Medical Center, Nashville, Tennessee; Department of Surgery, Vanderbilt University Medical Center, Nashville, Tennessee. Electronic address: ken.s.lau@vanderbilt.edu.

Funding

Vanderbilt-Ingram Cancer Center SPORE in Gastrointestinal CancerP50CA236733 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI STEPHEN W. FESIK · 2019 to 2026
$19.6M
Project 3 - Differential contribution of thymic APCs to central tolerance during the perinatal to adult transitionP01AI139449 · NIAID · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI RICHIE, ELLEN R · 2020 to 2024
$12.0M
Shaping the Microenvironment by DPEP1 Facilitates Adenoma ProgressionU54CA274367 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Qi Liu · 2022 to 2026
$9.7M
A Multimodal 3D Atlas of Colorectal Cancer Across Ages of OnsetU01CA294527 · NCI · VANDERBILT UNIVERSITY · PI LAU, KEN S, SPRAGGINS, JEFFREY M · 2024 to 2025
$5.2M
Tuft cell heterogeneity in function, lineage, and structure in ileal inflammatory diseaseR01DK103831 · NIDDK · VANDERBILT UNIVERSITY · PI LAU, KEN S · 2016 to 2024
$4.4M
NCI NIH HHS P50 CA236733NCI NIH HHS U01 CA294527NCI NIH HHS U54 CA274367NIAID NIH HHS P01 AI139449NIDDK NIH HHS R01 DK103831
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID42595207
PMCPMC13635945

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.