Evidence map›Paper›PMID 42594326›Full record

ReviewJCO global oncology2026

Worldwide Innovative Network Consortium: Building a Common Global Cancer Database.

Farhood Farahnak, Wafik S El-Deiry, Yves A Lussier, Razelle Kurzrock, Shai Magidi, Catherine Bresson, Shirin A Enger, Jia Liu, Jair Bar, Jeremy L Warner and 40 more

Abstract readReview
In one paragraph

Review in JCO global oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

50 authors.

Farhood FarahnakMcGill University Centre for Translational Research in Cancer and Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada.ORCID 0009-0002-3484-0641
Wafik S El-DeiryWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.
Yves A LussierDepartment of Biomedical Informatics, and Huntsman Cancer Center, University of Utah School of Medicine, Salt Lake City, UT.ORCID 0000-0001-9854-1005
Razelle KurzrockWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.ORCID 0000-0003-4110-1214
Shai MagidiWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.
Catherine BressonWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.ORCID 0000-0002-7523-849X
Shirin A EngerMcGill University Centre for Translational Research in Cancer and Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada.ORCID 0000-0002-6037-0615
Jia LiuProCan, Children's Medical Research Institute, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0003-4442-6516
Jair BarJusidman Cancer Center, Sheba Medical Center, Ramat Gan, Israel.ORCID 0000-0002-1224-3646
Jeremy L WarnerLegorreta Cancer Center at Brown University, Providence, RI.ORCID 0000-0002-2851-7242
Tobias MeissnerAvera Cancer Institute, Sioux Falls, SD.ORCID 0000-0002-9680-7153
Eitan RubinBen-Gurion University of the Negev, Be'er Sheva, Israel.ORCID 0000-0002-7807-4005
Jens RueterThe Jackson Laboratory, The Maine Cancer Genomics Initiative, Bar Harbor, ME.ORCID 0000-0002-9021-025X
Himabindu GaddipatiVyas Cancer Research (VCR Park), Maharanipeta, Visakhapatnam, Andhra Pradesh, India.
Mandar KulkarniVyas Cancer Research (VCR Park), Maharanipeta, Visakhapatnam, Andhra Pradesh, India.ORCID 0009-0006-6988-7940
Zhen ChenFudan University Shanghai Cancer Center, Shanghai, China.
Sewanti LimayeSir H.N. Reliance Foundation Hospital and Research Centre, Mumbai, India.ORCID 0000-0002-2170-5187
Rachel ElseyAvera Cancer Institute, Sioux Falls, SD.ORCID 0000-0003-2325-3775
Brenda M RubensteinLegorreta Cancer Center at Brown University, Providence, RI.ORCID 0000-0003-1643-0358
Anthony M JoshuaThe Kinghorn Cancer Centre, St Vincent's Hospital, Darlinghurst, NSW, Australia.ORCID 0000-0001-5159-4580
Humaid O Al-ShamsiBurjeel Cancer Institute, Burjeel Medical City, Abu Dhabi, UAE.ORCID 0000-0003-3819-0500
Khaled M MusallamSir H.N. Reliance Foundation Hospital and Research Centre, Mumbai, India.ORCID 0000-0003-3935-903X
Fanny WunderWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.
Jacques RaynaudWorldwide Innovative Network (WIN) Association-WIN Consortium, Chevilly-Larue, France.
Guy BerchemCentre Hospitalier du Luxembourg, Luxembourg, Luxembourg.ORCID 0000-0003-0157-2257
Manon GantenbeinLuxembourg Institute of Health, Luxembourg, Luxembourg.ORCID 0000-0002-5178-4365
Amal Al OmariKing Hussein Cancer Center, Amman, Jordan.ORCID 0000-0001-7571-3097
Said DermimeNational Center for Cancer Care and Research Hamad Medical Corporation, Doha, Qatar.ORCID 0000-0002-5526-7496
Hikmat Abdel-RazeqKing Hussein Cancer Center, Amman, Jordan.ORCID 0000-0003-2833-6051
Pierre SaintignyDepartment of Medical Oncology, Centre Léon Bérard, Lyon, France.ORCID 0000-0002-8090-9323
Andrés CervantesDepartment of Medical Oncology, INCLIVA Biomedical Research Institute, University of Valencia, Valencia, Spain.ORCID 0000-0003-3806-3691
Roger R ReddelProCan, Children's Medical Research Institute, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0002-6302-6107
Adel T ArefProCan, Children's Medical Research Institute, The University of Sydney, Sydney, NSW, Australia.ORCID 0000-0003-3028-131X
Juan Martin-LiberalCatalan Institute of Oncology, Barcelona, Spain.ORCID 0000-0003-2552-5172
Conxi LázaroCatalan Institute of Oncology, Barcelona, Spain.ORCID 0000-0002-7198-5906
David Cordero RomeraCatalan Institute of Oncology, Barcelona, Spain.ORCID 0000-0003-1470-2356
Marina SekachevaFederal State Autonomous Educational Institution of Higher Education I.M.Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation, Sechenovskiy University, Moscow, Russian Federation.
Raanan BergerJusidman Cancer Center, Sheba Medical Center, Ramat Gan, Israel.
C S PrameshTata Memorial Centre, Affiliated to Homi Bhabha National Institute, National Cancer Grid, Mumbai, India.ORCID 0000-0002-3635-0083
Ioana Berindan-NeagoeUniversity of Medicine and Pharmacy Iuliu Hatieganu, Cluj, Romania.ORCID 0000-0001-5828-1325
Eugenia GirdaRutgers Cancer Institute, New Brunswick, NJ.
Alejandro Piris-GimenezVall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.
Carol J FarhangfarWake Forest University Health Sciences/Atrium Health (WFUHS), Winston-Salem, NC.ORCID 0000-0001-9189-983X
Mohammed E SalemWake Forest University Health Sciences/Atrium Health (WFUHS), Winston-Salem, NC.ORCID 0000-0002-3661-6785
Rodrigo DienstmannVall d'Hebron Institute of Oncology (VHIO), Barcelona, Spain.ORCID 0000-0001-5997-318X
Ramon SalazarMedical Oncology Department, Oncobell Program IDIBELL Institut Català d'Oncologia (ICO) Duran i Reynals Hospital, Clinical Sciences Department, Bellvitge Campus, University of Barcelona. CIBERONC, Barcelona, Spain.ORCID 0000-0001-9419-6232
Naftali Z FrankelCHAIM Medical Resource Organization, New York, NY.
Zachary BatistSchool of Population and Global Health McGill University, Montreal, QC, Canada.ORCID 0000-0003-0435-508X
Yuri QuintanaBeth Israel Deaconess Medical Center, Boston, MA.ORCID 0000-0001-6583-0257
Gerald BatistMcGill University Centre for Translational Research in Cancer and Segal Cancer Centre, Jewish General Hospital, Montreal, QC, Canada.

Funding

SWOG Network Group Operations Center of the NCTNU10CA180888 · NCI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI PRIMO N. LARA · 2014 to 2026
$152.1M
Medical College of Wisconsin Lead Academic Participating Site RenewalUG1CA233198 · NCI · MEDICAL COLLEGE OF WISCONSIN · PI William H Bradley, Elizabeth M Gore · 2019 to 2026
$5.0M
NCI NIH HHS U10 CA180888NCI NIH HHS UG1 CA233198
6 · The paper itself

Abstract

This review shares the ongoing work of the global Worldwide Innovative Network (WIN) Consortium for Precision Medicine to synthesize emerging cancer treatment data and to define the requirements for a common global cancer database that can truly support precision oncology. We performed a narrative review of emerging cancer treatment data, molecular profiling technologies, and existing clinicogenomic databases, focusing on how tumors are characterized, how subgroups are defined, and how demographic, lifestyle, and environmental factors are captured. The growth in molecular profiling technologies and the development of new targeted therapies are transforming cancer care. Tumors, regardless of tissue origin, are increasingly defined as composites of multiple, often rare, subgroups, each with distinct biology and likely response to specific therapies, based on multidimensional profiling of the tumor and its microenvironment. The solution lies in building vast databases that capture racial and ethnic diversity, reflected in genomic data, as well as diet and lifestyle factors that may have epigenetic impact on gene expression and post-translational modifications. A truly inclusive and informative data set must reflect global diversity, and there are multiple examples of demography-dependent differences in genomic signals. With members caring for and studying patients with cancer across five continents, WIN is actively exploring pathways to create a global cancer database, rich in clinical and molecular detail, granular enough for precise analysis, and large enough to power artificial intelligence-driven insights, provided appropriate data quality, validation, and governance frameworks are in place. This review surveys the current landscape and outlines practical paths forward to achieve this goal.

Indexed as

Databases, FactualNeoplasmsHumansPrecision Medicine

Identifiers

PMID42594326
PMCPMC13532739

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.