Evidence map›Paper›PMID 42594146›Full record

ArticlePloS one2026

Machine learning models for predicting the hardness of additively manufactured Polymethyl Methacrylate (PMMA) parts for biomedical applications.

Dhinakaran Veeman, Pradeep Castro Ponnuswamy, Murugan Vellaisamy, Shivashiga Aravind Kumar Mangayarkarasi, Jitendra Kumar Katiyar

Abstract read
In one paragraph

Article in PloS one, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Dhinakaran VeemanCentre for Additive Manufacturing, Chennai Institute of Technology, Chennai, India.
Pradeep Castro PonnuswamyCentre for Additive Manufacturing, Chennai Institute of Technology, Chennai, India.
Murugan VellaisamyCentre for Additive Manufacturing, Chennai Institute of Technology, Chennai, India.
Shivashiga Aravind Kumar MangayarkarasiCentre for Additive Manufacturing, Chennai Institute of Technology, Chennai, India.
Jitendra Kumar KatiyarManipal Institute of Technology, Manipal Academy of Higher Education, Manipal, India.ORCID https://orcid.org/0000-0002-4189-9484

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Additively fabricated Polymethyl Methacrylate (PMMA) is highly preferred for medical applications. Its biocompatibility makes it the preferred material for biomedical applications such as prosthetics and dentistry. It is crucial to understand the mechanical properties of such materials when used in biomedical applications. Determining the mechanical properties of parts is a time-consuming and costly process. Additive manufacturing involves various process parameters that directly influence the mechanical properties of the fabricated parts. Hence, relying on traditional methods to determine the mechanical properties of additively fabricated parts would be ineffective. With advancements in technology, optimizing the process parameters for additive manufacturing of components would simplify the manufacturing process. Similarly, to determine the mechanical properties of materials, technological advancements must be integrated with additive manufacturing. Although non-destructive tests exist, they have limited applications and are too costly. This investigation analyses the feasibility of using machine learning models to predict the hardness of additively fabricated polymethyl methacrylate. Layer height, infill density, infill pattern, and raster orientation or infill line direction strongly influence mechanical properties and are considered variable input process parameters. The influence of each parameter on the hardness of the material is described. The machine learning models are evaluated using metrics to determine the best-fit model. This investigation would help medical experts determine the most suitable process parameters for additively fabricating Polymethyl Methacrylate parts for biomedical applications. Additionally, this investigation would help experts vary the hardness of biomedical parts according to the requirements or specific applications.

Indexed as

Biocompatible MaterialsMachine LearningPolymethyl MethacrylateHardnessMaterials TestingPredictive Learning ModelsBiocompatible MaterialsPolymethyl Methacrylate

Identifiers

PMID42594146
PMCPMC13472405

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.