Evidence map›Paper›PMID 42593886›Full record

ArticleAmerican journal on intellectual and developmental disabilities2026

Clinical Relevance of NIH Toolbox Cognition Battery Developmental Change in Intellectual and Developmental Disabilities: Associations with Verbal Reasoning.

Andrew Dakopolos, Numfon Vilay, Iris Chen, Aaron J Kaat, Emma Condy, Jeanine Coleman, Elizabeth Berry-Kravis, Craig Erickson, Audrey Thurm, David Hessl

Abstract read
In one paragraph

Article in American journal on intellectual and developmental disabilities, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew DakopolosUniversity of California, Davis MIND Institute, Sacramento, CA.ORCID 0000-0002-7175-6046
Numfon VilayUniversity of California, Davis MIND Institute, Sacramento, CA.
Iris ChenUniversity of California, Davis MIND Institute, Sacramento, CA.
Aaron J KaatNorthwestern University Feinberg School of Medicine, Chicago, IL.
Emma CondyHofstra University, Hempstead, NY.
Jeanine ColemanRegis University, Denver, CO.
Elizabeth Berry-KravisRush University Medical Center, Chicago, IL.
Craig EricksonCincinnati Children's Hospital Medical Center, Cincinnati, OH.
Audrey ThurmNational Institutes of Health, Bethesda, MD.
David HesslUniversity of California, Davis MIND Institute, Sacramento, CA.

Funding

Research Project: Pathologic Significance of Maternal AutoantibodiesP50HD103526 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI LEONARD J. ABBEDUTO, Melissa Dawn Bauman · 2020 to 2026
$9.7M
A Cognitive Test Battery for Intellectual DisabilitiesR01HD076189 · NICHD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI DAVID R HESSL · 2014 to 2026
$8.6M
NCBDD CDC HHS U50 DD000596NICHD NIH HHS P50 HD103526NICHD NIH HHS R01 HD076189
6 · The paper itself

Abstract

The NIH Toolbox Cognition Battery (NIHTB-CB) assesses crystallized verbal skills,and shows strong psychometric properties and sensitivity to developmental change in intellectual and developmental disabilities. However, whether gains in NIHTB-CB Crystallized Cognition reflect improvements in broader verbal abilities is unclear, and this has implications for clinical interpretation of the measure in the context of treatment studies. Two-hundred sixty-three participants completed NIHTB-CB Crystalized Cognition subtests (Picture Vocabulary, Oral Reading Recognition) and Stanford-Binet 5th ed. subtests (Verbal Knowledge, Verbal Fluid Reasoning) at baseline and at two-year follow-up. Bivariate latent change score models examined whether changes in Crystalized Cognition were related to changes in broader verbal skills. Changes in Crystalized Cognition were significantly related to changes in Verbal Knowledge (β = 7.92,

Indexed as

Developmental DisabilitiesIntellectual DisabilityNeuropsychological TestsPsychometricsThinkingAdolescentAdultChildFemaleHumansMaleNational Institutes of Health (U.S.)United StatesYoung Adultcognitiondown syndromefragile X syndromeLanguageoutcome measure

Identifiers

PMID42593886
PMCPMC13473730

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.