ArticleJournal of radiation research2026
A patch-based bolus technique for total scalp irradiation: dosimetric impact of conformity and reproducibility.
Article in Journal of radiation research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Total scalp irradiation (TSI) for scalp angiosarcoma remains technically challenging because of the large, highly curved target geometry and the need for reliable bolus application. This study aimed to develop a practical method to improve bolus conformity using commercially available bolus and to evaluate the dosimetric impact of bolus reproducibility in volumetric-modulated arc therapy (VMAT)-based TSI. An anthropomorphic head phantom was used to simulate TSI conditions. A three-segment 'patch bolus' method was developed to enhance conformity and setup stability. Treatment plans were generated using HyperArc with identical optimization parameters for three conditions: virtual bolus, single-sheet bolus and patch bolus. To assess reproducibility, the patch bolus was reapplied and rescanned 10 times, and dose distributions were recalculated on each dataset after rigid registration to isolate bolus-related variations. The patch bolus method substantially reduced air gaps compared with the single-sheet approach and achieved target coverage comparable to the virtual bolus condition. In contrast, the single-sheet bolus resulted in inferior coverage in regions with poor contact. Repeated application of the patch bolus demonstrated high reproducibility, with variations within 2% for most dose-volume metrics. Although relative variations exceeding 5% were observed for the lens, absolute doses remained low and clinically negligible. These findings indicate that VMAT-based TSI is relatively robust against minor bolus variations. The proposed patch bolus method provides improved conformity, reproducibility and workflow efficiency, representing a simple and clinically feasible strategy for TSI using external beam radiotherapy.
Indexed as
Identifiers
42593762What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.