ArticleJournal of neuro-oncology2026
The scientific evolution of the Ommaya reservoir: a bibliometric analysis.
Article in Journal of neuro-oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSince its introduction in 1963, the Ommaya reservoir has expanded beyond its original role as a ventricular access device to support intrathecal therapeutics, cerebrospinal fluid diagnostics, and emerging applications in precision neuro-oncology. To our knowledge, the evolution of this research landscape has not been quantitatively characterized.
methodsWe analyzed Web of Science Core Collection publications on June 19, 2026, retrieving 896 articles, of which 862 were included (English, unique DOI, complete metadata). Bibliometric analyses included publication trends, author impact, international collaboration mapping, keyword co-occurrence networks with spectral clustering, temporal overlay visualization, and abstract n-gram analysis. Analyses were performed in MATLAB v2025a.
resultsOutput increased from 1 to 3 articles annually in the 1960-1970 s to a peak of 67 in 2024, with nearly 90% of publications appearing within the past two decades. The United States contributed 323 publications (37.5%) and was the central collaboration hub. Four dominant themes emerged: neuro-oncology and intrathecal therapeutics, hydrocephalus and device-related complications, craniopharyngioma management, and surgical techniques with drug delivery. N-gram analysis revealed rapid emergence of "liquid biopsy" and "immunotherapy" in recent abstracts. Temporal analyses demonstrated a progressive shift in research from ventricular drug delivery toward cerebrospinal fluid biomarkers, molecular diagnostics, immunotherapy, and targeted therapeutics.
conclusionsOmmaya reservoir research has evolved from ventricular access and intrathecal drug delivery toward molecular diagnostics and precision neuro-oncology. Rather than reflecting device changes, these trends illustrate the expanding role of cerebrospinal fluid as both a therapeutic and diagnostic compartment in modern neuro-oncology.
Indexed as
Identifiers
42593704What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.