Evidence map›Paper›PMID 42593671›Full record

ArticleStrabismus2026

Quantitative analysis of binocular alignment by Hess screen testing in surgery for superior oblique palsy.

Qi Wei, Thomas Chang, Andrew Ryan, Amad Qureshi, Ningshi Yao, Ben Seiyon Lee, Wei-Yu Lai, Veronika Yehezkeli, Joseph L Demer

Abstract read
In one paragraph

Article in Strabismus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Qi WeiDepartment of Bioengineering, George Mason University, Washington, DC.
Thomas ChangDepartment of Bioengineering, George Mason University, Washington, DC.
Andrew RyanDepartment of Bioengineering, George Mason University, Washington, DC.
Amad QureshiDepartment of Bioengineering, George Mason University, Washington, DC.
Ningshi YaoDepartment of Bioengineering, George Mason University, Washington, DC.
Ben Seiyon LeeDepartment of Statistics, George Mason University, Washington, DC.
Wei-Yu LaiDepartment of Ophthalmology, University of California Los Angeles David Geffen School of Medicine.
Veronika YehezkeliDepartment of Ophthalmology, University of California Los Angeles David Geffen School of Medicine.
Joseph L DemerDepartment of Ophthalmology, University of California Los Angeles David Geffen School of Medicine.ORCID 0000-0001-9662-5352

Funding

Vision Research Core at UCLAP30EY000331 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Xian-Jie Yang · 1985 to 2026
$16.8M
BIOMECHANICAL ANALYSIS IN STRABISMUS SURGERYR01EY008313 · NEI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOSEPH Louis DEMER · 1991 to 2026
$15.0M
Data-Driven Biomechanical Simulation of Eye Movement and StrabismusR01EY029715 · NEI · GEORGE MASON UNIVERSITY · PI WEI, QI · 2019 to 2022
$1.5M
NEI NIH HHS P30 EY000331NEI NIH HHS R01 EY008313NEI NIH HHS R01 EY029715
6 · The paper itself

Abstract

purposeConventional prism-cover strabismus measurement is compromised by nonstandard and poorly repeatable target locations. We developed a general method to quantify incomitant strabismus in repeatable, defined gazes and illustrate its application to commonly performed surgical strategies in anatomically confirmed cases of superior oblique (SO) palsy.

methodsHess screen alignment data were obtained before, 1 week, and 3-7 months after surgery in 19 patients with unilateral SO atrophy demonstrated by magnetic resonance imaging. Five underwent ipsilateral inferior oblique (IO) recession, four contralateral inferior rectus (IR) recession, and 10 underwent both. An automated program measured scanned Hess charts at 21 fixation targets at ±15° and 30° horizontal and vertical eccentricities for each fixating eye. Heat maps were created across the fixation field, quantifying strabismus angles, surgical effects, and secular trends. Individual heat maps were pointwise averaged for affected and fellow eyes, and according to the type of surgery: ipsilateral IO recession, contralateral IR recession, and combined.

resultsPre-operative alignment maps demonstrated three incomitant hypertropia patterns addressed by distinct surgical approaches. Recession of the IR alone produced immediate and stable correction of hypertropia with minimal incomitant effect. Recession of the IO corrected large lateral incomitance and had progressively improving late effects. Combining these approaches corrected lateral incomitance and hypertropia in infraversion, with progressively improving late effect.

conclusionAlignment heat maps allow intuitive visualization of selective strabismus surgical strategies treating varied incomitance in SO palsy, reflecting progressive improvement in alignment when surgery includes IO recession.

Indexed as

Hess screen testhypertropiainferior oblique musclestrabismusstrabismus surgerysuperior oblique muscle

Identifiers

PMID42593671
PMCPMC13641720

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.