Evidence map›Paper›PMID 42593516›Full record

ArticleEuropean journal of applied physiology2026

Sedentary behaviour and step count are related to skeletal muscle insulin sensitivity in young adult normal-weight women without regular exercise habits: an accelerometer and doubly labelled water method study.

Hibiki Aikawa, Yoichi Hatamoto, Eiichi Yoshimura, Takuro Tobina, Makoto Ayabe, Yuko Ichida, Masaki Kato, Hideaki Kumahara

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Hibiki AikawaGraduate School of Nutritional Sciences, Nakamura Gakuen University, 5-7-1 Befu, Jounan-ku, Fukuoka, 814-0198, Japan.ORCID http://orcid.org/0009-0008-0195-3985
Yoichi HatamotoCenter for Clinical Nutrition, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health, and Nutrition, 3-17, Shin-machi-Senrioka, Settsu, Osaka, 566-0002, Japan.ORCID http://orcid.org/0000-0002-7254-2568
Eiichi YoshimuraCenter for Clinical Nutrition, National Institute of Health and Nutrition, National Institutes of Biomedical Innovation, Health, and Nutrition, 3-17, Shin-machi-Senrioka, Settsu, Osaka, 566-0002, Japan.ORCID http://orcid.org/0000-0003-3722-668X
Takuro TobinaFaculty of Nursing and Nutrition, University of Nagasaki, 1-1-1 Manabino, Nagayo-cho, Nishi-Sonogi-gun, Nagasaki, 851-2195, Japan.ORCID http://orcid.org/0000-0003-4789-2563
Makoto AyabeFaculty of Computer Science and Systems Engineering, Okayama Prefectural University, 111 Kuboki, Soja, Okayama, 719-1197, Japan.
Yuko IchidaFood and Health Innovation Center, Nakamura Gakuen University, 5-7-1 Befu, Jounan-ku, Fukuoka, 814-0198, Japan.
Masaki KatoFood and Health Innovation Center, Nakamura Gakuen University, 5-7-1 Befu, Jounan-ku, Fukuoka, 814-0198, Japan.
Hideaki KumaharaFood and Health Innovation Center, Nakamura Gakuen University, 5-7-1 Befu, Jounan-ku, Fukuoka, 814-0198, Japan. kumahara@nakamura-u.ac.jp.ORCID http://orcid.org/0000-0003-4223-8490

Funding

Japan Society for the Promotion of Science JP19H04023
6 · The paper itself

Abstract

purposeLifestyle habits in young adult women and health maintenance are crucial for lifelong disease prevention in middle-aged and older adults. Evidence regarding associations between free-living physical activity (PA) and glucose tolerance in non-underweight, non-overweight young adult women remains limited. We examined associations between glucose tolerance-related blood markers and PA indices, including intensity-specific PA and energy expenditure variables, using validated objective measures in normal-weight young adult women without an exercise habit.

methodsThis exploratory cross-sectional study enrolled 28 healthy young adult women (22 ± 2 years; body mass index, 20.9 ± 2.3 kg/m

resultsThe mean PA level was 1.58 ± 0.16, corresponding to a low-to-moderate range. Fasting blood test values did not indicate impaired glucose tolerance. In single correlation analyses, MISI demonstrated significant negative correlation with %SB (rs =  - 0.455, p = 0.015, 95% CI =  - 0.761 to - 0.042) and positive correlation with step counts (rs = 0.490, p = 0.008, 95% CI = 0.155 to 0.739). Conversely, HIRI showed no association with PA indices.

conclusionLower time spent in SB and a greater number of daily steps were associated with higher muscle insulin sensitivity, even in healthy normal-weight young adult women.

Indexed as

Energy expenditureExercise intensityInsulin resistanceJapaneseSitting

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.