ArticleEuropean journal of applied physiology2026
Sedentary behaviour and step count are related to skeletal muscle insulin sensitivity in young adult normal-weight women without regular exercise habits: an accelerometer and doubly labelled water method study.
Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeLifestyle habits in young adult women and health maintenance are crucial for lifelong disease prevention in middle-aged and older adults. Evidence regarding associations between free-living physical activity (PA) and glucose tolerance in non-underweight, non-overweight young adult women remains limited. We examined associations between glucose tolerance-related blood markers and PA indices, including intensity-specific PA and energy expenditure variables, using validated objective measures in normal-weight young adult women without an exercise habit.
methodsThis exploratory cross-sectional study enrolled 28 healthy young adult women (22 ± 2 years; body mass index, 20.9 ± 2.3 kg/m
resultsThe mean PA level was 1.58 ± 0.16, corresponding to a low-to-moderate range. Fasting blood test values did not indicate impaired glucose tolerance. In single correlation analyses, MISI demonstrated significant negative correlation with %SB (rs = - 0.455, p = 0.015, 95% CI = - 0.761 to - 0.042) and positive correlation with step counts (rs = 0.490, p = 0.008, 95% CI = 0.155 to 0.739). Conversely, HIRI showed no association with PA indices.
conclusionLower time spent in SB and a greater number of daily steps were associated with higher muscle insulin sensitivity, even in healthy normal-weight young adult women.
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