Evidence map›Paper›PMID 42593490›Full record

ArticleAesthetic plastic surgery2026

Psychosocial and Socioeconomic Determinants of Stigma in Facial Localized Scleroderma.

Jiangmiao Xie, Shi Xiang, Jiayue Zhu, Zenan Xia, Jiuzuo Huang, Ang Zeng, Nanze Yu, Linjuan Tan, Xuda Ma, Xiaojun Wang and 1 more

Abstract read
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Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

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0 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jiangmiao XieDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Shi XiangOperating Room, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Jiayue ZhuDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Zenan XiaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Jiuzuo HuangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Ang ZengDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Nanze YuDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Linjuan TanOperating Room, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China.
Xuda MaDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China. 1476580863@qq.com.ORCID http://orcid.org/0000-0002-5112-6186
Xiaojun WangDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China. pumchwxj@163.com.
Xiao LongDepartment of Plastic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Shuaifuyuan 1#, Dongcheng District, Beijing, 100730, People's Republic of China. pumclongxiao@126.com.

Funding

Beijing Natural Science Foundation of China L244061Beijing Natural Science Foundation of China L244062Beijing Natural Science Foundation of China L254044Innovative Research Group Project of the National Natural Science Foundation of China 82302828Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences and Peking Union Medical College No.UBJ11557Medical and Health Science Innovation Project of the Chinese Academy of Medical Sciences No. 2021-I2M-1-068National Natural Science Foundation of China 82472565Peking Union Medical College Hospital Talent Cultivation Program (Category B) No.UGG10110
6 · The paper itself

Abstract

backgroundFacial localized scleroderma (LoS) often results in visible disfigurement and stigma, yet factors contributing to stigma in this population remain insufficiently characterized.

objectiveTo identify clinical, psychosocial, and socioeconomic factors associated with stigma in patients with facial LoS.

methodA cross-sectional study was conducted between June 2023 and June 2025 at a tertiary dermatology and plastic surgery center in China. Patients aged ≥ 12 years with stable facial LoS completed validated questionnaires assessing appearance satisfaction (FACE-Q), social support (SSRS), and stigma (Stigma Scale for Chronic Illness). Clinical and socioeconomic data were collected, and multivariate regression was used to identify independent predictors of stigma.

resultsOf 159 eligible patients, 123 completed the survey (mean age, 24.3 years; 66.7% female). Overall appearance satisfaction was low (FACE-Q mean, 47.8 ± 19.89). Higher stigma scores were independently associated with labial involvement, lower FACE-Q scores, and reduced social support. Lack of health insurance predicted greater intrinsic stigma, whereas residence outside first-tier cities was associated with higher extrinsic stigma. Disease severity (LoSDI) was not associated with stigma. Most patients reported limited awareness of reconstructive options, with dermatologists serving as the primary source of information.

conclusionsStigma in facial LoS is driven primarily by appearance dissatisfaction, inadequate social support, and socioeconomic disparities rather than clinical disease severity. These findings highlight stigma as a critical component of disease burden and support the need for multidisciplinary, patient-centered care integrating psychosocial support and improved access to reconstructive interventions. LEVEL OF EVIDENCE III: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266.

Indexed as

Facial disfigurementLocalized sclerodermaPsychosocial factorsReconstructive surgerySocioeconomic statusStigma

Identifiers

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Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.