Evidence map›Paper›PMID 42593380›Full record

ArticleJACC. Case reports2026

A Giant Free-Floating Left Atrial Thrombus With a Flipper Effect.

Lorenzo Niro, Gianluca Sclafani, Teresa Cammelli, Anna Maria Traini, Riccardo Codecasa, Pierluigi Stefano, Anna Toso

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lorenzo NiroCardiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Prato, Italy. Electronic address: lorenzo.niro92@gmail.com.
Gianluca SclafaniCardiac Surgery, Careggi University Hospital, Florence, Italy.
Teresa CammelliCardiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Prato, Italy.
Anna Maria TrainiCardiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Prato, Italy.
Riccardo CodecasaCardiac Surgery, Careggi University Hospital, Florence, Italy.
Pierluigi StefanoCardiac Surgery, Careggi University Hospital, Florence, Italy.
Anna TosoCardiology Unit, Department of Medical Specialties, Azienda USL Toscana Centro, Prato, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft atrial (LA) masses may be diagnostically challenging in patients with atrial fibrillation, previous mitral valve surgery, and severe LA remodeling. CASE SUMMARY: A 77-year-old woman with permanent atrial fibrillation and a bileaflet mechanical mitral prosthesis underwent pacemaker implantation. Predischarge transthoracic echocardiography revealed a large LA mass. Transesophageal echocardiography showed a heterogeneous mobile mass, raising the differential diagnosis of thrombus vs myxoma. After intravenous unfractionated heparin, repeat transesophageal echocardiography demonstrated a giant free-floating mass intermittently impinging on the prosthetic discs without increased transprosthetic gradients. Contrast-enhanced computed tomography showed no postcontrast enhancement. Urgent surgery removed the mass, which was macroscopically consistent with thrombus. DISCUSSION: Serial transesophageal echocardiography, particularly with 3-dimensional imaging, can identify dynamic changes in mass mobility and guide prompt management before embolic or prosthetic obstructive complications occur. TAKE-HOME MESSAGE: A free-floating LA thrombus near a mechanical mitral prosthesis may require urgent surgery despite normal gradient.

Indexed as

cardiac thrombusleft atrial massmechanical mitral valvemyxomaprosthetic valvetransesophageal echocardiography

Identifiers

PMID42593380
PMCPMC13669932

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.