Evidence map›Paper›PMID 42593374›Full record

ArticleJACC. Case reports2026

Delayed Aortic Embolization of a Left Atrial Appendage Occlusion Device: Implications for Risk-Stratified Postprocedural Management.

Ryan J Mackey, Alec Miller, Leonard Palatnic, Sina Salehi Omran, Stanley F Fernandez, Vijay S Iyer, Mohamed Y Abdel-Aal Ahmed

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan J MackeyDepartment of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA. Electronic address: rjmackey@buffalo.edu.
Alec MillerDivision of Cardiology, Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Leonard PalatnicDivision of Cardiology, Department of Medicine, University at Buffalo Jacobs School of Medicine and Biomedical Sciences, Buffalo, New York, USA.
Sina Salehi OmranBuffalo General Medical Center, Gates Vascular Institute, Buffalo, New York, USA.
Stanley F FernandezBuffalo General Medical Center, Gates Vascular Institute, Buffalo, New York, USA.
Vijay S IyerBuffalo General Medical Center, Gates Vascular Institute, Buffalo, New York, USA.
Mohamed Y Abdel-Aal AhmedBuffalo General Medical Center, Gates Vascular Institute, Buffalo, New York, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundLeft atrial appendage occlusion (LAAO) is an established alternative to long-term anticoagulation for stroke prevention in select patients with atrial fibrillation. Device embolization is rare, most commonly occurring intraprocedurally or within 24 hours. CASE SUMMARY: A 67-year-old man with paroxysmal atrial fibrillation underwent successful implantation of a Watchman FLX device. Eighteen days later, while shoveling snow, he developed sudden-onset chest and back pain followed by bilateral lower extremity paralysis. Computed tomography revealed complete mid-abdominal aortic occlusion from embolization of the LAAO device. Despite emergent endovascular retrieval and restoration of aortic flow, the patient developed fatal distributive shock from severe ischemia-reperfusion injury. DISCUSSION: This case illustrates a rare but clinically significant presentation of delayed device embolization. This patient possessed multiple National Cardiovascular Data Registry-identified risk factors for postdischarge device embolization, indicating that current risk stratification protocols may not be adequate for patients with device embolization risk factors. TAKE-HOME MESSAGES: Risk-stratified protocols with extended activity restrictions and earlier postprocedure surveillance imaging warrant investigation in patients with National Cardiovascular Data Registry-identified risk factors for postdischarge LAAO device embolization.

Indexed as

atrial fibrillationcomplicationrisk factor

Identifiers

PMID42593374
PMCPMC13689865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.