Evidence map›Paper›PMID 42593297›Full record

ArticleTheScientificWorldJournal2026

The Role of IGF-1 and IL-10 in Childhood Stunting: Evidence From Indonesia.

Putriatri Krimasusini Senudin, Irwanto, Nur Aisiyah Widjaja, Sulistiawati

Abstract read
In one paragraph

Article in TheScientificWorldJournal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Putriatri Krimasusini SenudinDoctoral Program of Medical Science, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0003-3822-4301
IrwantoDepartment of Child Health, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0002-7573-8793
Nur Aisiyah WidjajaDepartment of Child Health, Faculty of Medicine, Universitas Airlangga, Dr. Soetomo General Academic Hospital, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0002-4253-8760
SulistiawatiDepartement of Public Health and Preventive Medicine, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia, unair.ac.id.ORCID https://orcid.org/0000-0001-7907-5598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Stunting remains a pressing public health problem in low- and middle-income countries. The specific biochemical roles of growth- and immune-related biomarkers with stunting are less understood. This study is aimed at investigating the contribution of insulin-like growth factor 1 (IGF-1) and interleukin-10 (IL-10) to stunting among Indonesian children. A case-control design was employed involving 80 children aged 24-60 months in Manggarai, Indonesia (40 stunted and 40 nonstunted), matched by age, sex, and residence. Data were collected through anthropometric measurements, household surveys, structured interviews, and biochemical analysis of serum IGF-1 and IL-10 using ELISA. Findings revealed that stunted children had significantly lower IGF-1 levels (11.963 ± 8.658 vs. 18.000 ± 15.238, p < 0.05) and higher IL-10 levels (317.841 ± 214.934 vs. 543.605 ± 416.837, p < 0.05) compared with controls. The study concludes that effective stunting prevention requires integrated interventions addressing both nutritional adequacy and infection control in early childhood.

Indexed as

Growth DisordersInsulin-Like Growth Factor IInterleukin-10BiomarkersCase-Control StudiesChild, PreschoolFemaleHumansIndonesiaMaleBiomarkersIL10 protein, humanInsulin-Like Growth Factor IInterleukin-10child growthearly childhoodIGF-1IL-10nutritional statusstunting

Identifiers

PMID42593297
PMCPMC13471639

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.