Evidence map›Paper›PMID 42593119›Full record

ArticlemBio2026

PRRSV suppresses FTO-dependent

Yipeng Pang, Fructueux Modeste Amona, Yuan Liang, Xiaohan Chen, Ran Tao, Zilu Liu, Shiqing Yang, Yuenan Wang, Wenxin Chen, Xinchi Xia and 5 more

Abstract read
In one paragraph

Article in mBio, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yipeng Pang *School of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.ORCID 0009-0008-5468-1215
Fructueux Modeste Amona *School of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.ORCID 0000-0002-3436-4553
Yuan Liang *School of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Xiaohan Chen *School of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Ran TaoInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.ORCID 0000-0001-9458-0285
Zilu LiuSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Shiqing YangSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Yuenan WangSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Wenxin ChenSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Xinchi XiaSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Rong ZhouSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.
Bin LiInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.ORCID 0000-0003-1318-7081
Baochao FanInstitute of Veterinary Medicine, Jiangsu Academy of Agricultural Sciences, Nanjing, China.ORCID 0000-0001-9780-5080
Xingtang FangSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.ORCID 0000-0002-4013-9950
Xi ChenSchool of Life Science, Institute of Cellular and Molecular Biology, Jiangsu Normal University, Xuzhou, Jiangsu, China.ORCID 0009-0006-4574-6166

Funding

National Key Research and Development Program of China 2025YFF1000800National Natural Science Foundation of China 32000108National Natural Science Foundation of China 32373030Natural Science Foundation of Jiangsu Province 20201022
6 · The paper itself

Abstract

RNA viruses have evolved diverse strategies to evade host interferon (IFN)-stimulated gene (ISG) defenses; however, how they exploit host epitranscriptomic regulation remains poorly understood. Here, we identify an immune-evasion mechanism in which porcine reproductive and respiratory syndrome virus (PRRSV) targets the

Indexed as

AdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTOHost-Pathogen InteractionsImmune EvasionImmunity, InnatePorcine Reproductive and Respiratory SyndromePorcine respiratory and reproductive syndrome virusSignal TransductionSTAT Transcription FactorsAnimalsDemethylationEpitranscriptomeEpitranscriptomicsRNA MethylationSwineAdenosineAlpha-Ketoglutarate-Dependent Dioxygenase FTON-methyladenosineSTAT Transcription FactorsepitranscriptomicsFTOinnate immunityinterferon signalingm6A modificationPRRSV

Identifiers

PMID42593119
PMCPMC13556206

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.