Evidence map›Paper›PMID 42592798›Full record

ArticleeLife2026

Nucleation-dependent propagation of Polycomb modifications emerges during the

Natalie Gonzaga-Saavedra, Eleanor A Degen, Isabella V Soluri, Corinne Croslyn, Shelby A Blythe

Abstract read
In one paragraph

Article in eLife, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Breaking anterior-posterior symmetry in the moth flybioRxiv : the preprint server for biology · 2025
    Article
  8. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Natalie Gonzaga-SaavedraInterdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, United States.
Eleanor A DegenInterdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, United States.
Isabella V SoluriDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.
Corinne CroslynInterdisciplinary Biological Sciences Graduate Program, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0002-9190-7390
Shelby A BlytheDepartment of Molecular Biosciences, Northwestern University, Evanston, United States.ORCID https://orcid.org/0000-0003-4986-2579

Funding

CELLULAR &MOLECULAR BASIS OF DISEASE TRAINING PROGRAMT32GM008061 · NIGMS · NORTHWESTERN UNIVERSITY · PI CARTHEW, RICHARD W. · 1985 to 2022
$17.1M
Defining epigenetic mechanisms for embryonic patterningR01HD101563 · NICHD · NORTHWESTERN UNIVERSITY · PI Shelby Alexander Blythe · 2021 to 2026
$2.0M
National Science Foundation Graduate Research Fellowship Program DGE-2234667NICHD NIH HHS R01 HD101563NIGMS NIH HHS T32 GM008061NIH HHS R01 HD101563NIH HHS T32 GM008061
6 · The paper itself

Abstract

During zygotic genome activation in

Indexed as

DrosophilaDrosophila melanogasterDrosophila ProteinsPolycomb-Group ProteinsProtein Processing, Post-TranslationalZygoteAnimalsGene Expression Regulation, DevelopmentalHistonesDrosophila ProteinsHistonesPolycomb-Group Proteinschromatinchromosomesdevelopmental biologyD. melanogasterembryonic developmentepigeneticsgene expressionpolycomb

Identifiers

PMID42592798
PMCPMC13472630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.