ArticleOrthopedic reviews2026
The impact of depression on outcomes in revision knee replacement surgery.
Article in Orthopedic reviews, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
0 citing papers in PubMed.
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Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Revision total knee arthroplasty is associated with more variable functional recovery and greater postoperative burden than primary surgery. Depression may influence recovery, but its effect in revision knee replacement remains incompletely defined. Objective: To synthesise evidence on the association between depression or poor preoperative mental health and outcomes after revision total knee arthroplasty. Methods: PubMed, MEDLINE, and Embase were searched on August 12, 2025. Adult revision total knee arthroplasty studies assessing depression or mental health in relation to postoperative outcomes were eligible. Owing to heterogeneity in exposure definitions, outcomes, and follow-up, findings were narratively synthesised. Results: Of 103 records identified, 44 duplicates were removed and 59 records screened; 6 studies were included. Depression or poorer preoperative mental health was associated with worse postoperative function, persistent pain, greater narcotic analgesic use, lower satisfaction, infection, reoperation or re-revision, readmission, emergency department attendance, prolonged stay, non-home discharge, and higher costs. However, patients with poorer mental health could still achieve clinically meaningful functional improvement. Conclusion: Depression is associated with poorer outcomes after revision total knee arthroplasty but should not be considered a contraindication to surgery. Mental health recognition, expectation-setting, and multidisciplinary optimisation may improve perioperative care.
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