ArticleJournal of family medicine and primary care2026
Escalating threat of multidrug-resistant bacteria: Insights from a low-middle income country setting.
Article in Journal of family medicine and primary care, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Infections due to multidrug-resistant bacteria have become a global threat, increasing morbidity, mortality and healthcare costs. The main drivers for antimicrobial resistance are indiscriminate antimicrobial use, poor drug quality and lack of antimicrobial stewardship programs. Aim: This one-year prospective study aimed to determine the prevalence of multidrug-resistant bugs among hospital-acquired infections (HAI) in a low-middle income country. Methods: Depending on the clinical suspicion, various samples were processed as per standard protocols. Multiple antibiotic resistance (MAR) index was calculated, and isolates were characterized into multi-/extensively/pan-drug resistant isolates (MDR/ XDR/ PDR). Results: Nosocomial bacterial infections were identified in 13% patients which yielded 165 isolates (85% Gram-negative). 89.6% of these GN isolates were MDR, 77.5% of which were XDR and 2.8% PDR. Conclusion: By prioritizing infection control measures, early detection and judicious empirical antimicrobial use, healthcare facilities can significantly reduce the risk of HAIs and ensure a safer environment for patients.
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