Evidence map›Paper›PMID 42592490›Full record

ArticleActa pharmaceutica Sinica. B2026

Mussel-inspired biphasic microneedle patch for long-acting hypothyroidism treatment.

Wen Zhang, Hanqing Liu, Jinxuan Hou, Kai Lei, Jiapeng Lei, Yinli Jin, Chuang Chen, Jianying Huang, Wei Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wen ZhangClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Hanqing LiuDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jinxuan HouDepartment of Thyroid and Breast Surgery, Zhongnan Hospital of Wuhan University, Wuhan 430071, China.
Kai LeiClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Jiapeng LeiClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Yinli JinClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Chuang ChenDepartment of Breast and Thyroid Surgery, Renmin Hospital of Wuhan University, Wuhan 430060, China.
Jianying HuangClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.
Wei LiClinical Trial Center of Zhongnan Hospital, School of Pharmaceutical Sciences, Wuhan University, Wuhan 430071, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypothyroidism, caused by insufficient thyroid hormone production or impaired responsiveness, is typically managed with lifelong daily oral levothyroxine sodium (LT

Indexed as

Bioadhesive hydrogelBiphasicHypothyroidism treatmentLevothyroxine sodiumLong-actingMicroneedleSustained releaseTransdermal drug delivery

Identifiers

PMID42592490
PMCPMC13464087

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.