ArticleAME case reports2026
ALK-rearranged lung adenocarcinoma transforming to mucoepidermoid carcinoma in a 45-year-old female: a case report.
Article in AME case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Pulmonary mucoepidermoid carcinoma (PMEC) accounts for less than 1% of pulmonary malignancies and is predominantly primary, exhibiting distinct clinical manifestations and treatment responses compared to lung adenocarcinoma (LUAD). Although the incidence of histological transformation from non-small cell lung cancer (NSCLC) to small cell lung cancer (SCLC) following tyrosine kinase inhibitor (TKI) therapy is approximately 3-14%, transformation from LUAD to PMEC is an extremely rare event. Currently, there is a lack of unified understanding and diagnostic/therapeutic guidelines concerning its mechanism, clinical features, treatment strategies, and prognosis. This article reports a case of HT from LUAD to PMEC following anaplastic lymphoma kinase ( Case Description: This report describes a 45-year-old female patient who was admitted to the hospital with a chief complaint of "persistent cough, sputum production, and dyspnea for 2 years, accompanied by chest tightness for 1 week". She was diagnosed with Conclusions: Tumors that undergo LUAD-to-PMEC transformation after
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