ArticleTransplantation direct2026
Cryopreservation Maintains Structural Integrity and Biomechanical Properties of Human Rectus Fascia for up to 1 mo.
Article in Transplantation direct, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Immunosuppression-free Nonvascularized Rectus Fascia Allotransplantation for Complex Hernia Repair.Transplantation direct · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Abdominal wall closure after transplantation is crucial to reduce morbidity and to ensure graft and patient survival, but it often remains challenging. Donor nonvascularized rectus fascia (NVRF) allotransplantation offers a valuable solution when primary closure fails. Despite the growing clinical use of NVRF, standardized protocols for NVRF preservation are lacking. This study evaluates the impact of short-term cold storage at 4 °C (8 d) and long-term cryopreservation (1 mo and 6 mo) on human NVRF at the mechanical, histological, and microbiological levels. Methods: NVRF was obtained from 10 human donors (6 men; 6 donation after circulatory death III; 4 donation after brain death; age 56 y [26-68 y]; BMI 28 kg/m Results: After 8 d at 4 °C, ultimate strength and rigidity were reduced, whereas histological structure appeared intact. One month of cryopreservation showed no indications for altered mechanical or histological characteristics compared with fresh tissue. After prolonged cryopreservation for 6 mo, extensibility was increased. Yeast contamination was absent in all samples, and commensal bacteria were detected in 17 of 40 fresh and preserved samples, without impact of the preservation method. Conclusions: In conclusion, cryopreservation at -80 °C maintains biomechanical characteristics and structural integrity of NVRF for up to 1 mo, offering a promising method for prolonged NVRF preservation in clinical applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.