Evidence map›Paper›PMID 42592306›Full record

ArticleCureus2026

Heart-Shaped Subhyaloid Haemorrhage in Valsalva Retinopathy With Successful Delayed Minimally Invasive Management.

Shamim Choudhury, Adhikari Dissakaruna, Hallam Amos, Jai Shankar

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Shamim ChoudhuryEmergency Department, Betsi Cadwaladr University Health Board, Wrexham, GBR.
Adhikari DissakarunaOphthalmology, Base Hospital Marawila, Marawila, LKA.
Hallam AmosOphthalmology, Aneurin Bevan University Health Board, Cardiff, GBR.
Jai ShankarOphthalmology, Wrexham Maelor Hospital, Wrexham, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Valsalva retinopathy is a recognised cause of acute painless visual loss resulting from a sudden increase in intrathoracic or intra-abdominal pressure, leading to subhyaloid haemorrhage. While most reported cases describe rounded or boat-shaped haemorrhages, atypical morphologies documented with multimodal imaging are infrequently reported. We describe a 45-year-old female with long-standing insulin-treated diabetes mellitus who developed sudden visual blurring following a violent coughing episode. Fundoscopic examination revealed a sharply demarcated, heart-shaped subhyaloid haemorrhage involving the macula, and optical coherence tomography confirmed a subhyaloid haemorrhage. Despite intervention occurring almost three weeks after symptom onset, intravitreal tissue plasminogen activator combined with expansile gas resulted in significant anatomical and functional recovery, with visual acuity improving from 6/36 to 6/9 and sustained improvement on follow-up. This case highlights the importance of recognising atypical haemorrhage morphology, accurately localising haemorrhage depth using optical coherence tomography, and individualising management. It also demonstrates that delayed minimally invasive intervention may achieve excellent visual outcomes, even in the presence of pre-existing retinal disease.

Indexed as

diabetic retinopathyexpansile gasintravitreal tpaoptical coherence tomographypremacular haemorrhagepreretinal haemorrhagesubhyaloid haemorrhagevalsalva retinopathy

Identifiers

PMID42592306
PMCPMC13464797

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.