Evidence map›Paper›PMID 42592170›Full record

ArticleActa pharmaceutica Sinica. B2026

IFI30 reprograms glioblastoma-associated macrophage and induces immune evasion by MAFF/PTGS2 pathway.

Sen Zhang, Wenlin Chen, Liwen Ren, Jie Yi, Xiangjin Zheng, Yihui Yang, Hong Yang, Guanhua Du, Wan Li, Yu Wang and 1 more

Abstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sen ZhangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Wenlin ChenDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
Liwen RenThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Jie YiDepartment of Clinical Laboratory, Peking Union Medical College Hospital, Beijing 100730, China.
Xiangjin ZhengDepartment of Pharmacy, Medical Supplies Center, Chinese PLA General Hospital, Beijing 100853, China.
Yihui YangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Hong YangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Guanhua DuThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Wan LiThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.
Yu WangDepartment of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.
Jinhua WangThe State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Beijing 100050, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In recent years, immunotherapy has shown obvious advantages in treating cancers. The close interaction between cancer cells and immune cells in the tumor microenvironment (TME) underlies the progression of glioblastoma multiforme (GBM). However, there are no effective immune-related targets against GBM. Here,

Indexed as

CD8 T cellDrug targetGlioblastoma multiformeIFI30Immune microenvironmentMacrophageMAFFPTGS2

Identifiers

PMID42592170
PMCPMC13464069

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.