Evidence map›Paper›PMID 42592020›Full record

Trial reportFrontiers in pain research (Lausanne, Switzerland)2026

Neurodynamic techniques vs. desensitization maneuvers in the manual therapy management of moderate carpal tunnel syndrome among women: randomized clinical trial with 1-year follow-up.

Mohamed I Mabrouk, Sahar A Abdalbary, Ehab A A El-Shaarawy, Sami Elmahgoub, Aseel Aburub, Mohammad Z Darabseh, Alexandra Makai, Pongrác Ács

Abstract readClinical Trial
In one paragraph

Trial report in Frontiers in pain research (Lausanne, Switzerland), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Mohamed I MabroukDepartment of Physiotherapy, Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.
Sahar A AbdalbaryDepartment of Orthopaedic Physical Therapy, Faculty of Physical Therapy, Nahda University, Beni Suef, Egypt.
Ehab A A El-ShaarawyDepartment of Anatomy and Embryology, Faculty of Medicine, Cairo University, Giza, Egypt.
Sami ElmahgoubDepartment of Physiotherapy, Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.
Aseel AburubDepartment of Physiotherapy, Faculty of Allied Medical Sciences, Applied Science Private University, Amman, Jordan.
Mohammad Z DarabsehDepartment of Physiotherapy, School of Rehabilitation Sciences, The University of Jordan, Amman, Jordan.
Alexandra MakaiInstitute of Physiotherapy and Sports Science, Faculty of Health Sciences, Pecsi Tudomanyegyetem Egeszsegtudomanyi Kar, Pécs, Hungary.
Pongrác ÁcsInstitute of Physiotherapy and Sports Science, Faculty of Health Sciences, Pecsi Tudomanyegyetem Egeszsegtudomanyi Kar, Pécs, Hungary.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aimed to compare the clinical and electrophysiological effects of neurodynamic techniques vs. desensitization maneuvers in women with moderate carpal tunnel syndrome (CTS). Design: Randomized clinical trial. The study included 380 female participants with moderate carpal tunnel syndrome, aged between 45 and 55 years, who were randomly assigned to a neurodynamic technique group or a desensitization maneuvers group. Neurodynamic techniques in one group and desensitization in the other group were conducted for 3 months. Outcome: Measures were nerve conduction, pain, symptom severity, and functional status using the Boston Carpal Tunnel Questionnaire, and cylindrical and pincer grip strength before treatment and after 3 months of treatment. One-year follow-up for pain, symptom severity, and functional status using the Boston Carpal Tunnel Questionnaire. Results: Both groups demonstrated significant within-group improvements in nerve conduction, pain, symptom severity, and functional status ( Conclusion: Both interventions were effective in women with moderate CTS; however, desensitization maneuvers demonstrated superior improvements in neurophysiological outcomes, pain, and function over 12 weeks, with sustained benefits at 1-year follow-up.

Indexed as

carpal tunnel syndromecervical spinedesensitisationmanual therapynerve conduction 3

Identifiers

PMID42592020
PMCPMC13463407

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.