Evidence map›Paper›PMID 42591918›Full record

ArticleOpen forum infectious diseases2026

Parallel Declines in Human Papillomavirus 6/11-Related Disease Incidences: A National Study of Anogenital Warts and Recurrent Respiratory Papillomatosis in Norway.

Madleen Orumaa, Ståle Nygård, Joseph Tota, Parag Mahale, Thea Eline Hetland Falkenthal

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Madleen OrumaaDepartment of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.ORCID https://orcid.org/0000-0001-6849-202X
Ståle NygårdDepartment of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.ORCID https://orcid.org/0000-0002-5263-4748
Joseph TotaDepartment of Epidemiology, Biostatistics and Research Decision Sciences, MRL, Merck & Co., Inc., Rahway, New Jersey, USA.ORCID https://orcid.org/0009-0007-9630-260X
Parag MahaleDepartment of Epidemiology, Biostatistics and Research Decision Sciences, MRL, Merck & Co., Inc., Rahway, New Jersey, USA.
Thea Eline Hetland FalkenthalDepartment of Research, Cancer Registry of Norway, Norwegian Institute of Public Health, Oslo, Norway.ORCID https://orcid.org/0009-0009-0198-0761

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anogenital warts and recurrent respiratory papillomatosis are conditions caused by human papillomavirus (HPV) types 6/11 that can be prevented by vaccination. We analyzed Norwegian national registry data (2010-2023) to assess the impact of the 4-valent HPV vaccine introduced in 2009. Anogenital warts incidence among females aged 15-29 decreased significantly from 1120.0 to 280.6 per 100 000 (annual percentage change: -10.3%), paralleling a sharp decline in recurrent respiratory papillomatosis from 3.7 to 0.6 per 100 000 (annual percentage change: -11.3%). These results strongly support vaccination impact in reducing the burden of HPV 6/11-related diseases, suggesting successful interruption of transmission pathways and substantial population-level protection.

Indexed as

AGWAoRRPJoRRPquadrivalent HPV vaccineRRP

Identifiers

PMID42591918
PMCPMC13463632

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.